882304-31-6

Basic information

• Product Name: 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-ol
• Synonyms: 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-ol
• CAS NO: 882304-31-6
• Molecular Weight: 414.641
• Mol File: 882304-31-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-ol(882304-31-6)
• EPA Substance Registry System: 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-ol(882304-31-6)

Safety Data

• Hazardous Substances Data: 882304-31-6(Hazardous Substances Data)

Upstream product

• 56041-85-1 4-ethynylthioanisole 
• 97315-18-9 p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 124153-81-7 2-methyl-4-[4-(methylsulfanyl)phenyl]-3-butyn-2-ol 
• 104-95-0 (4-bromophenyl)thioanisole 

Downstream Products

• 869384-78-1 3-(4-methylsulfanylphenyl)-1-(3-hydroxy-4-methoxyphenyl)prop-2-yn-1-one 
• 869384-76-9 3-(4-methylsulfanylphenyl)-1-[3-(tert-butyldimethylsilyloxy)-4-methoxyphenyl]prop-2-yn-1-one 

Relevant articles and documents

Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: Dual inhibitors of cyclooxygenases and lipoxygenases

A group of 1,3-diarylprop-2-yn-1-ones (13, 17, 23, 26 and 27) possessing a C-3 p-SO2Me COX-2 pharmacophore were designed, synthesized and evaluated as potential dual inhibitors of cyclooxygenase-1/2 (COX-1/2) and 5/15-lipoxygenases (5/15-LOX) t