88315-63-3

Basic information

• Product Name: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline
• Synonyms: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline
• CAS NO: 88315-63-3
• Molecular Weight: 237.301
• Mol File: 88315-63-3.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(88315-63-3)
• EPA Substance Registry System: (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline(88315-63-3)

Safety Data

• Hazardous Substances Data: 88315-63-3(Hazardous Substances Data)

Usage

Description

(E)-4-methoxy-N-((E)-3-phenylallylidene)aniline, also known as Vanillin Aniline, is a chemical compound characterized by the presence of a methoxy group, an allylidene group, and an aniline group. This versatile molecule is widely utilized in the synthesis of organic compounds and pharmaceuticals, showcasing its significance in various industries.

Uses

Used in Fragrance Industry:
(E)-4-methoxy-N-((E)-3-phenylallylidene)aniline is used as a fragrance component in the perfumery industry for its distinctive and appealing scent. Its incorporation enhances the overall aroma of perfumes, contributing to their unique and attractive fragrance profiles.
Used in Flavor Industry:
In the food and beverage sector, (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline serves as a flavoring agent, adding depth and complexity to the taste of various products. Its use in this industry is attributed to its ability to impart a pleasant and desirable flavor, enhancing the overall sensory experience of consumable goods.
Used in Pharmaceutical Industry:
(E)-4-methoxy-N-((E)-3-phenylallylidene)aniline holds potential in the pharmaceutical industry as a key intermediate in the development of new drugs. Its unique chemical structure allows for the creation of novel therapeutic agents, addressing various medical needs and contributing to the advancement of pharmaceutical research.
However, it is crucial to exercise caution when handling (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline due to its potential hazards and harmful effects if not used or stored properly. Proper safety measures and guidelines should be followed to ensure the safe and effective utilization of this chemical compound in various applications.

Upstream product

• 104-94-9 4-methoxy-aniline 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 100-17-4 para-methoxynitrobenzene 
• 104-54-1 3-Phenylpropenol 
• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 2101-87-3 p-methoxy-phenylazide 
• 22774-93-2 N-cinnamyl-4-methoxybenzenamine 

Downstream Products

• 160191-70-8 (R)-N-(4-methoxyphenyl)-α-methylbenzenepropenamine 
• 298693-05-7 (S)-N-(4-methoxyphenyl)-α-methylbenzenepropenamine 
• 84209-24-5 cis-1-p-methoxyphenyl-3-phthalimido-4-styrylazetidin-2-one 
• 200428-42-8 (4-Methoxy-phenyl)-[(R)-1-((E)-styryl)-pentyl]-amine 
• 132931-51-2 3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-(4-methoxy-phenyl)-5-((E)-styryl)-4,5-dihydro-[1,2,4]oxadiazole 
• 122127-12-2 6-(4-Methoxy-phenyl)-3-phenyl-2-p-tolyl-3,6-dihydro-2H-[1,2,6]thiadiazine 1-oxide 
• 76553-81-6 (4-Methoxy-phenyl)-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-amine; compound with trichloro-acetic acid 
• 51-66-1 4-methoxyacetanilide 
• 87025-18-1 N-(4-Methoxy-phenyl)-N-((E)-3-phenyl-allyl)-acetamide 
• 132931-41-0 4-(4-Methoxy-phenyl)-5-((E)-styryl)-3-(2,4,6-trimethyl-phenyl)-4,5-dihydro-[1,2,4]oxadiazole 
• 108908-70-9 cis-1-(p-anisyl)-3-phenoxy-4-styrylazetidin-2-one 
• 122127-24-6 6-(4-Methoxy-phenyl)-2,3-diphenyl-3,6-dihydro-2H-[1,2,6]thiadiazine 1-oxide 

Relevant articles and documents

A Novel ZnII Complex Bearing Two Monodentate (4-Methoxyphenyl)[(1E, 2E)-3-phenylprop-2-en-1-ilidene] Schiff Bases: Crystal Structure and DFT Study

A novel ZnII complex bearing two monodentate (4-methoxyphenyl)[(1E, 2E)-3-phenylprop-2-en-1-ilidene] Schiff bases was synthesized and investigated both in the solid state by single-crystal X-ray diffraction, elemental analysis, and FTIR and in

Iron-Catalyzed Hydrogen Transfer Reduction of Nitroarenes with Alcohols: Synthesis of Imines and Aza Heterocycles

A straightforward and selective reduction of nitroarenes with various alcohols was efficiently developed using an iron catalyst via a hydrogen transfer methodology. This protocol led specifically to imines in 30-91% yields, with a good functional group tolerance. Noticeably, starting from o-nitroaniline derivatives, in the presence of alcohols, benzimidazoles can be obtained in 64-72% yields when the reaction was performed with an additional oxidant, DDQ, and quinoxalines were prepared from 1,2-diols in 28-96% yields. This methodology, unprecedented at iron for imines, also provides a sustainable alternative for the preparation of quinoxalines and benzimidazoles.

Stereoselective Construction of γ-Lactams via Copper-Catalyzed Borylacylation

A versatile and highly stereoselective borylative cyclization to generate polyfunctionalized γ-lactams has been developed. The stereoselective synthesis of these key ring systems is crucial due to their ubiquity in natural products. We report the diastero- and enantioselective construction of di- and trisubstituted γ-lactam cores, with examples containing an enantioenriched quaternary carbon.