883874-55-3

Basic information

• Product Name: 1-Piperazinebutanenitrile, 4-(2-fluorophenyl)-
• CAS NO: 883874-55-3
• Molecular Formula: C14H18FN3
• Molecular Weight: 247.315
• Mol File: 883874-55-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Piperazinebutanenitrile, 4-(2-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinebutanenitrile, 4-(2-fluorophenyl)-(883874-55-3)
• EPA Substance Registry System: 1-Piperazinebutanenitrile, 4-(2-fluorophenyl)-(883874-55-3)

Safety Data

• Hazardous Substances Data: 883874-55-3(Hazardous Substances Data)

Upstream product

• 1011-15-0 1-(o-fluorophenyl)piperazine 
• 5332-06-9 4-bromobutanenitrile 

Downstream Products

• 883874-56-4 4-(4-(2-fluorophenyl)piperazin-1-yl)butan-1-amine 
• 937742-32-0 (E)-N-{4-[4-(2-fluorophenyl)piperazin-1-yl]butyl}-3-(4-nitrophenyl)acrylamide 

Relevant articles and documents

Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands

Isosteric replacement of the amide function and modulation of the arylpiperazine moiety of known dopamine D3 receptor ligands led to potent and selective compounds. Enhanced bioavailability and preferential brain distribution make compound 6c a good candi

3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands

The invention relates to 3,4-dihydro-2-naphthamide derivatives of formula (I), pharmaceutical compositions containing them and their therapeutic applications as partial agonists or antagonists of the dopamine D3 receptor for the treatment of neuropsychological disorders.