884305-08-2

Basic information

• Product Name: Hydroxy Ziprasidone
• Synonyms: Hydroxy Ziprasidone;5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]-1-hydroxyethyl]-6-chloro-1,3-dihydro-2H-indol-2-one;Ziprasidone BC
• CAS NO: 884305-08-2
• Molecular Formula: C₂₁H₂₁ClN₄O₂S
• Molecular Weight: 428.93504
• EINECS: -0
• Mol File: 884305-08-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Heated)
• CAS DataBase Reference: Hydroxy Ziprasidone(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxy Ziprasidone(884305-08-2)
• EPA Substance Registry System: Hydroxy Ziprasidone(884305-08-2)

Safety Data

• Hazardous Substances Data: 884305-08-2(Hazardous Substances Data)

Usage

Description

Hydroxy Ziprasidone is an impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. It is characterized by its ability to modulate neurotransmitter activity, which contributes to its potential applications in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
Hydroxy Ziprasidone is used as an impurity in the production of Ziprasidone, which is an antipsychotic medication. Its presence, although as an impurity, is significant for the development and formulation of antipsychotic drugs that target the serotonin and dopamine receptors to manage various psychiatric conditions.

Upstream product

• 884305-06-0 6-chloro-5-(2-chloro-1-hydroxyethyl) indolin-2-one 
• 87691-87-0 3-(1-piperazinyl)-1,2-benzisothiazole 
• 118289-55-7 6-chloro-5-(2-chloroethyl)-2-oxindole 
• 118307-04-3 6-chloro-5-(2-chloroacetyl) indolin-2-one 

Relevant articles and documents

Ziprasidone process

A process for preparing ziprasidone having low levels of keto ziprasidone and hydroxy ziprasidone impurities.