884495-36-7

Basic information

• Product Name: 6-Chloro-3-formyl-2-picoline
• Synonyms: 2-Methyl-6-chloropyridine-3-carboxaldehyde;6-Chloro-3-formyl-2-picoline;6-Chloro-2-methyl-3-pyridinecarboxaldehyde;6-Chloro-2-methylnicotinaldehyde;6-Chloro-2-methyl-pyridine-3-carboxaldehyde;6-Chloro-2-Methyl-pyridine-3-carbaldehyde;3-Pyridinecarboxaldehyde, 6-chloro-2-Methyl-
• CAS NO: 884495-36-7
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.58
• Product Categories: Pyridine
• Mol File: 884495-36-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 256.728 °C at 760 mmHg
• Flash Point: 109.065 °C
• Appearance: /
• Density: 1.27 g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 6-Chloro-3-formyl-2-picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-3-formyl-2-picoline(884495-36-7)
• EPA Substance Registry System: 6-Chloro-3-formyl-2-picoline(884495-36-7)

Safety Data

• Hazardous Substances Data: 884495-36-7(Hazardous Substances Data)

Usage

Uses

6-Chloro-3-formyl-2-picoline can be used as plasma kallikrein inhibitors.

InChI:InChI=1/C7H6ClNO/c1-5-6(4-10)2-3-7(8)9-5/h2-4H,1H3

Upstream product

• 66909-36-2 6-chloro-2-methyl-3-pyridinecarbonitrile 
• 132606-40-7 3-bromo-6-chloro-2-methyl-pyridine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 926296-40-4 [4-(5-formyl-6-methyl-pyridin-2-ylsulfanyl)-phenyl]-acetic acid methyl ester 
• 926305-03-5 [4-(5-formyl-6-methyl-pyridin-2-yloxy)-phenylsulfanyl]-acetic acid tert-butyl ester 
• 926303-58-4 6-(4-bromo-2-methyl-phenylsulfanyl)-2-methyl-pyridine-3-carbaldehyde 
• 926305-17-1 N-cyclopropyl-4-(5-formyl-6-methyl-pyridin-2-yloxy)-benzamide 
• 1150617-08-5 N-{4-[(5-formyl-6-methyl-2-pyridinyl)thio]phenyl}methanesulfonamide 
• 1150617-12-1 N-[2-(ethyloxy)ethyl]-4-[(5-formyl-6-methyl-2-pyridinyl)amino]-3-methylbenzamide 
• 1093879-95-8 (6-chloro-2-methylpyridin-3-yl)methanol 
• 106984-91-2 6-oxo-1,6-dihydropyridine-3-carbaldehyde 
• 439111-18-9 1-(6-chloro-2-methylpyridin-3-yl)ethan-1-one 
• 7631-86-9 SiO₂ 

Relevant articles and documents

NITROGEN HETEROARYL DERIVATIVE HAVING CSF1R INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

This application describes a nitrogen heteroaryl derivative having CSF1R inhibitory activity, and a preparation method therefor and an application thereof. Compounds in the present invention has a structure represented by formula (I) as below, and the definition on substituents is as stated in the description and the claims. The compounds in the this application can be widely applied to preparation of drugs for treating cancer, tumor, autoimmune disease, metabolic disease, or metastatic disease, in particular ovarian cancer, pancreatic cancer, prostate cancer, breast cancer, cervical cancer, glioblastoma, multiple myeloma, metabolic disease, neurodegenerative disease, metastasis of primary tumor sites, or osseous metastatic cancer, and a new generation of CSF1R inhibitor drugs is expected to be developed.

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).