884845-06-1

Basic information

• Product Name: (R)-1H-1-(2-nitrophenyl)perfluorooctan-1-ol
• CAS NO: 884845-06-1
• Molecular Weight: 521.183
• Mol File: 884845-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1H-1-(2-nitrophenyl)perfluorooctan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1H-1-(2-nitrophenyl)perfluorooctan-1-ol(884845-06-1)
• EPA Substance Registry System: (R)-1H-1-(2-nitrophenyl)perfluorooctan-1-ol(884845-06-1)

Safety Data

• Hazardous Substances Data: 884845-06-1(Hazardous Substances Data)

Upstream product

• 577-19-5 2-nitrophenyl bromide 
• 376-27-2 methyl perfluorooctanoate 
• 884845-05-0 1-(2-nitrophenyl)perfluorooctan-1-one 

Downstream Products

• 884845-07-2 (R)-1H-1-(2-aminophenyl)perfluorooctan-1-ol 
• 835624-45-8 (R)-1-bromo-2-(1-hydroxy-1H-perfluorooctyl)benzene 

Relevant articles and documents

Asymmetric reduction of perfluoroalkyl ketones with chiral lithium alkoxides

Reduction of perfluoroalkyl ketones with chiral lithium alkoxides gave chiral α-perfluoroalkyl alcohols in high enantiomeric excesses. Interestingly, reaction of 2,2,2-trifluoroacetophenone (1) with lithium (S)-1-phenylethoxide (2) gave (S)-2,2,2-trifluoro-1-phenylethanol (3), while the same reaction of perfluorooctan-1-one (7) with 2 gave (R)-1H-1- phenylperfluorooctanol (8). Based on the speculation of mechanism, the order of steric effects on this reaction is estimated as C7F15 > substituted phenyl > CF3.