885-91-6

Basic information

• Product Name: Imidazo[1,2-a]pyridine, 7-methyl-2-phenyl-
• Synonyms: Imidazo[1,2-a]pyridine, 7-methyl-2-phenyl-
• CAS NO: 885-91-6
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.25848
• Mol File: 885-91-6.mol
• Article Data: 56

Chemical Properties

• Melting Point: 174 °C
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• PKA: 7.32±0.50(Predicted)
• CAS DataBase Reference: Imidazo[1,2-a]pyridine, 7-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine, 7-methyl-2-phenyl-(885-91-6)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine, 7-methyl-2-phenyl-(885-91-6)

Safety Data

• Hazardous Substances Data: 885-91-6(Hazardous Substances Data)

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 75-52-5 nitromethane 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 4636-16-2 iodoacetophenone 
• 613-91-2 acetophenone oxime 
• 19433-17-1 acetophenone O-acetyloxime 
• 100-41-4 ethylbenzene 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 100-42-5 styrene 
• 13466-41-6 4-methyl-1H-pyridin-2-one 
• 102921-26-6 (1,2-dibromoethyl)benzene 
• 108-89-4 picoline 
• 16717-64-9 1-azidostyrene 

Downstream Products

• 65964-48-9 2-phenyl-7-(trans-2-thiophen-2-yl-vinyl)-imidazo[1,2-a]pyridine 
• 65964-65-0 7-methyl-2,3-dibenzimidazo[1,2-α]pyridine 
• 1310492-79-5 7-methyl-2-phenyl-3-(phenylthio)-imidazo[1,2-a]pyridine 

Relevant articles and documents

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

Regioselective C-H dithiocarbamation of indolizines with tetraalkylthiuram disulfide under metal-free conditions

An efficient and straightforward metal-free regioselective C-H dithiocarbamation of indolizines with tetraalkylthiuram disulfide has been described. A series of indolizine-dithiocarbamate derivatives were easily accessed in moderate to good yields with a broad scope. In addition, imidazo[1,2-a]pyridines were also well tolerated to afford diverse imidazoheterocycle-dithiocarbamate products, which are expected to be utilized for drug discovery. Of note, the reaction could be readily scaled up, and shows its practical value in organic synthesis.

Imidazopyridine compound, pharmaceutical composition containing the same, and preparation method and application thereof (by machine translation)

Specifically discloses a pharmaceutical composition containing the compound and a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate [1,2 - a] of the compound, and the preparation method, comprises the following steps of inhibiting, protein selectivity, drug effect strong STAT3 patent medicine, safety and the like, and the like . is particularly suitable for preventing and, or treating tumor growth and metastasis as well as pharmaceutical composition and pharmaceutical acceptable salt or pharmaceutically acceptable salt or pharmaceutically acceptable solvate of the compound in preparing STAT3 high-expression cell abnormal proliferation, form change and exercise function hyperthyroidism, and other related diseases / and are disclosed in the present invention. (by machine translation)