885225-87-6

Basic information

• Product Name: 7-bromo-1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole
• Synonyms: 7-bromo-1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole
• CAS NO: 885225-87-6
• Molecular Weight: 354.169
• Mol File: 885225-87-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-bromo-1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole(885225-87-6)
• EPA Substance Registry System: 7-bromo-1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole(885225-87-6)

Safety Data

• Hazardous Substances Data: 885225-87-6(Hazardous Substances Data)

Upstream product

• 883001-24-9 7-bromo-5-fluoro-3-methyl-1H-indole 
• 85118-01-0 alpha-bromo-3,4-difluorotoluene 

Downstream Products

• 885225-92-3 1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole-7-carboxylic acid ethyl ester 
• 885225-89-8 1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indole-7-carbonitrile 
• 885225-88-7 4-[1-(3,4-difluoro-benzyl)-5-fluoro-3-methyl-1H-indol-7-yl]-phenylamine 

Relevant articles and documents

A general approach to indole-7-yl derivatives of isoxazole, oxadiazole, thiadiazole and pyrazole

Isosteric replacement of the α,β-unsaturated amide at the C-7 position of indoles with a diverse set of five-membered amino-heterocycles including isoxazole, oxadiazole, thiadiazole and pyrazole followed by subsequent derivatization of the heterocyclic amino group to yield amides, sulfonamides and phosphoramides is described. Distinctive features of these procedures include the versatility and robust nature of the synthetic steps along with the high yields of the targeted molecules.