885273-81-4 Usage
Description
5,7-DICHLORO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE, with the chemical abstracts service number 885273-81-4, is a chemical compound that plays a significant role in the synthesis of cyclic benzolactams. It is involved in electrophilic aromatic substitution reactions of carbamoyl cations, which are crucial for the preparation of these benzolactams. Additionally, it has potential applications in agriculture, as it may enhance stress tolerance in plants against abiotic stress, thereby promoting plant growth and increasing yield.
Uses
Used in Pharmaceutical Industry:
5,7-DICHLORO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE is used as a key intermediate in the synthesis of cyclic benzolactams, which are important for the development of pharmaceutical compounds with potential therapeutic applications.
Used in Agriculture:
5,7-DICHLORO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE is used as an active agent for enhancing stress tolerance in plants against abiotic stress. Its application aims to boost plant growth and increase plant yield, making it a valuable asset in agricultural practices for improving crop resilience and productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 885273-81-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 885273-81:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*3)+(2*8)+(1*1)=214
214 % 10 = 4
So 885273-81-4 is a valid CAS Registry Number.
885273-81-4Relevant articles and documents
Synthesis of Medium-Ring-Sized Benzolactams by Using Strong Electrophiles and Quantitative Evaluation of Ring-Size Dependency of the Cyclization Reaction Rate
Kurouchi, Hiroaki,Ohwada, Tomohiko
supporting information, p. 876 - 901 (2019/12/30)
Benzolactams with medium-sized rings were synthesized via the electrophilic aromatic substitution reaction of carbamoyl cations (R1R2N+═C═O) in good to high yields without dilution. These reactions were utilized to quantitatively examine the extent of retardation of medium-sized ring formation, compared to five- or six-membered ring formation. The order of reaction rates of formation of cyclic benzolactams is six- > five- > seven- > eight- > nine-membered ring at 25 °C. The present reaction provides a route to eight- A nd nine-membered benzolactams.
