885275-55-8 Usage
General Description
5-CHLORO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID is a chemical compound with a molecular formula C9H7ClN4O2. It is an imidazo[1,2-a]pyridine derivative that contains a chloro and a methyl group attached to the imidazole ring, as well as a carboxylic acid group. 5-CHLORO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID has potential as a pharmaceutical intermediate and building block for the synthesis of various biologically active molecules. It may also have applications in the development of new drugs for the treatment of certain diseases and disorders. Further research and investigation into the properties and potential uses of this chemical are warranted.
Check Digit Verification of cas no
The CAS Registry Mumber 885275-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 885275-55:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*5)+(2*5)+(1*5)=218
218 % 10 = 8
So 885275-55-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2O2/c1-5-8(9(13)14)12-6(10)3-2-4-7(12)11-5/h2-4H,1H3,(H,13,14)
885275-55-8Relevant articles and documents
Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents
Wang, Apeng,Lv, Kai,Li, Linhu,Liu, Hongtao,Tao, Zeyu,Wang, Bin,Liu, Mingliang,Ma, Chao,Ma, Xican,Han, Bing,Wang, Aoyu,Lu, Yu
, p. 715 - 725 (2019)
A series of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides (IPAs), based on the structure of WZY02 discovered in our lab, were designed and synthesized as new anti-TB agents. Results reveal that many of them exhibit excellent in vitro inhibitory activity with low nanomolar MIC values against both drug-sensitive MTB strain H37Rv and drug-resistant clinical isolates. Compounds 15b and 15d display good safety and pharmacokinetic profiles, suggesting their promising potential to be lead compounds for future antitubercular drug discovery.
