885280-00-2 Usage
General Description
6-Bromo-1H-benzimidazole-2-carboxylic acid methyl ester is a chemical compound with the molecular formula C9H6BrN3O2. It is a methyl ester derivative of 6-bromo-1H-benzimidazole-2-carboxylic acid and is commonly used in organic synthesis and pharmaceutical research. 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER is a white to off-white solid that is soluble in organic solvents such as DMSO and methanol. It is known to possess anti-inflammatory and antifungal properties, making it a potential candidate for the development of new medications. Additionally, 6-Bromo-1H-benzimidazole-2-carboxylic acid methyl ester has been found to exhibit inhibitory activity against certain enzymes, making it a valuable tool in biochemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 885280-00-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,8 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 885280-00:
(8*8)+(7*8)+(6*5)+(5*2)+(4*8)+(3*0)+(2*0)+(1*0)=192
192 % 10 = 2
So 885280-00-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrN2O2/c1-14-9(13)8-11-6-3-2-5(10)4-7(6)12-8/h2-4H,1H3,(H,11,12)
885280-00-2Relevant articles and documents
2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: Optimization of the tryptamine side chain
Young, Jonathan R.,Huang, Song X.,Walsh, Thomas F.,Wyvratt Jr., Matthew J.,Yang, Yi Tien,Yudkovitz, Joel B.,Cui, Jisong,Mount, George R.,Ren, Rena Ning,Wu, Tsuei-Ju,Shen, Xiaolan,Lyons, Kathryn A.,Mao, An-Hua,Carlin, Josephine R.,Karanam, Bindhu V.,Vincent, Stella H.,Cheng, Kang,Goulet, Mark T.
, p. 827 - 832 (2002)
A series of 2-arylindoles containing novel heteroaromatic substituents on the tryptamine tether, based on compound 1, was prepared and evaluated for their ability to act as gonadotropin releasing hormone (GnRH) antagonists. Successful modifications of 1 included chain length variation (reduction) and replacement of the pyridine with heteroaromatic groups. These alterations culminated in the discovery of compound 27kk which had excellent in vitro potency and oral efficacy in rodents.
