885412-71-5

Basic information

• Product Name: N-(α-methyl-4-ethylbenzyl)-p-toluenesulfonamide
• Synonyms: N-(α-methyl-4-ethylbenzyl)-p-toluenesulfonamide
• CAS NO: 885412-71-5
• Molecular Weight: 303.425
• Mol File: 885412-71-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(α-methyl-4-ethylbenzyl)-p-toluenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(α-methyl-4-ethylbenzyl)-p-toluenesulfonamide(885412-71-5)
• EPA Substance Registry System: N-(α-methyl-4-ethylbenzyl)-p-toluenesulfonamide(885412-71-5)

Safety Data

• Hazardous Substances Data: 885412-71-5(Hazardous Substances Data)

Upstream product

• 105-05-5 1,4-diethylbenzene 
• 70-55-3 toluene-4-sulfonamide 

Relevant articles and documents

Site-Selective Electrochemical Benzylic C?H Amination

C?H/N-H cross-coupling is an ideal strategy to synthesize various amines but remains challenging owing to the requirement for sacrificial chemical oxidants and the difficulty in controlling the regio- and chemo-selectivity. Herein we report a site-selective electrochemical amination reaction that can convert benzylic C?H bonds into C-N linkages via H2 evolution without need for external oxidants or metal catalysts. The synthetic strategy involves anodic cleavage of benzylic C?H to form a carbocation intermediate, which is then trapped with an amine nucleophile leading to C?N bond formation. Key to the success is to include HFIP as a co-solvent to modulate the oxidation potentials of the alkylbenzene substrate and the aminated product to avoid overoxidation of the latter.