88557-53-3

Basic information

• Product Name: Propanoic acid, 2-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (2R)-
• CAS NO: 88557-53-3
• Molecular Formula: C10H18O4
• Molecular Weight: 202.251
• Mol File: 88557-53-3.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (2R)-(88557-53-3)
• EPA Substance Registry System: Propanoic acid, 2-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (2R)-(88557-53-3)

Safety Data

• Hazardous Substances Data: 88557-53-3(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 80657-57-4 3-hydroxy-(2S)-methylpropionate 

Downstream Products

• 299430-04-9 (S)-2-methyl-4-phenylsulfonyl-1-tetrahydropyranyloxybutane 
• 127483-95-8 Benzoic acid (R)-1-[(R)-1-benzenesulfonyl-2-methyl-3-(tetrahydro-pyran-2-yloxy)-propyl]-2-methyl-2-(tetrahydro-pyran-2-yloxymethyl)-but-3-enyl ester 
• 107692-03-5 (2R,3R)-2-methyl-1-(tetrahydropyran-2-yloxy)butan-2-ol benzyl ether 
• 96882-99-4 2(S)-methyl-3-phenylsulfonyl-1,5(S)-hexanediol-1-THP ether 
• 96882-99-4 2(R)-methyl-3-phenylsulfonyl-1,5(R)-hexanediol-1-THP ether 
• 96882-96-1 (S)-2-methyl-3-phenylthio-1-propanol THP ether 
• 96947-44-3 (2R)-2-methyl-1-(phenylsulfanyl)-3-(tetrahydropyran-2-yloxy)propane 
• 96882-97-2 (S)-2-methyl-1-(phenylsulfonyl)-3-(tetrahydropyranyloxy)propane 
• 96947-45-4 (R)-2-methyl-1-(phenylsulfonyl)-3-(tetrahydropyranyloxy)propane 
• 109687-73-2 5(S)-<(tert-butoxycarbonyl)amino>-2(R)-methyl-6-<4-(phenylmethoxy)phenyl>-1-<(2-tetrahydropyranyl)oxy>-trans-3-hexene 
• 143236-59-3 2-[(S)-3-(4-Methoxy-benzyloxy)-2-methyl-propoxy]-tetrahydro-pyran 
• 165961-48-8 (4R)-<<5-(Tetrahydropyran-2-yloxy)-4-methyl-1-pentyl>oxy>(1,1-dimethylethyl)diphenylsilane 
• 65284-00-6 (R)-3-methyl-γ-butyrolactone 
• 88671-02-7 (R)-1-(benzyloxy)-2-methyl-3-[(tetrahydropyranyl)oxy]propan 

Relevant articles and documents

Oxysterols: 27-hydroxycholesterol and its radiolabeled analog

We describe a convenient and stereoselective route to the synthesis of 27-hydroxycholesterol. Also its radiolabeled analog, 22, 23 di [3H]-27-hydroxycholesterol with high specific radioactivity (55 Ci/mmol) was synthesized by this method. Julia

Enantioselective Synthesis and Activity of All Diastereoisomers of (E)-Phytal, a Pheromone Component of the Moroccan Locust, Dociostaurus maroccanus

The Moroccan locust, Dociostaurus maroccanus (Thunberg, 1815) (Orthoptera: Acrididae), is a polyphagous pest capable of inflicting large losses in agriculture under favorable environmental and climatic conditions. Currently, control of the pest relies solely on the application of conventional insecticides that have negative effects on the environment and human safety. In the search for a more rational, environmentally acceptable approach for locust control, we have previously reported that (Z/E)-phytal (1) is a male-produced candidate sex pheromone of this acridid. This molecule, with two stereogenic centers at C-7 and C-11, has four different diastereomers along with the Z/E stereochemistry of the double bond at C-2. In this paper, we present for the first time the enantioselective synthesis of the four diastereomers of (E)-phytal and their electrophysiological and behavioral activity on males and females. Our results demonstrate that the (R,R)-phytal is the most active diastereomer in both assays, significantly attracting females in a double-choice Y olfactometer, and confirming the previous chromatographic assignment as component of the sex pheromone of the Moroccan locust.

SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS

The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.