885619-01-2

Basic information

• Product Name: ethyl 5-amino-1-phenyl-1H-imidazole-4-carboxylate
• Synonyms: ethyl 5-amino-1-phenyl-1H-imidazole-4-carboxylate
• CAS NO: 885619-01-2
• Molecular Weight: 231.254
• Mol File: 885619-01-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl 5-amino-1-phenyl-1H-imidazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-amino-1-phenyl-1H-imidazole-4-carboxylate(885619-01-2)
• EPA Substance Registry System: ethyl 5-amino-1-phenyl-1H-imidazole-4-carboxylate(885619-01-2)

Safety Data

• Hazardous Substances Data: 885619-01-2(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 52579-16-5 ethyl N-(ethoxycarbonylcyanomethyl) formimidate 
• 64-17-5 ethanol 
• 155579-42-3 5-amino-1-phenyl-1H-imidazole-4-carbonitrile 
• 122-51-0 orthoformic acid triethyl ester 
• 32683-02-6 ethyl-2-aminocyano acetate 
• 6780-49-0 ethyl N-phenylformimidate 
• 105-56-6 ethyl 2-cyanoacetate 
• 78-39-7 Triethyl orthoacetate 

Downstream Products

• 885618-26-8 2-(4-bromo-phenyl)-1-(4-chloro-phenyl)-9-phenyl-1,9-dihydro-purin-6-one 
• 1019996-17-8 C₂₄H₁₇BrN₄O₂ 
• 1132702-97-6 C₃₀H₂₆N₃O₂P 
• 885614-45-9 1-(4-bromo-phenyl)-2-(4-methyl-phenyl)-9-phenyl-1,9-dihydro-purin-6-one 
• 5470-24-6 6-Chloro-9-phenyl-9H-purine 
• 6334-42-5 1,9-dihydro-9-phenyl-6H-purin-6-one 

Relevant articles and documents

Three-component condensation of 5-aminoimidazole derivatives with aldehydes and Meldrum's acid. Synthesis of 3,4,6,7-tetrahydroimidazo[4,5-b]pyridin-5-ones

A convenient method for the synthesis of the earlier unknown substituted 3,4,6,7-tetrahydroimidazo[4,5-b]pyridin-5-ones was developed based on a three-component condensation of 5-aminoimidazole derivatives, aldehydes, and Meldrum's acid. Unstable aminoimidazole derivatives were readily formed in situ by decarboxylation of 5-amino-4-imidazolecarboxylic acids in acidic medium at room temperature, whose sodium salts were obtained by the alkaline hydrolysis of the corresponding, readily available esters.

Efficient synthesis and biological evaluation of 1,2,9-trisubstituted 1,9-dihydro-6H-purin-6-ones

The carbodiimides 4, obtained from aza-Wittig reactions of iminophosphorane 3 with aromatic isocyanates, reacted with amines in the presence of a catalytic amount of RO-Na+ to give the 1,2,9-trisubstituted 1,9-dihydro-6H-purin-6-ones

COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).