886041-81-2

Basic information

• Product Name: methyl 14-cyclohexyl-7-[methyl(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate
• Synonyms: methyl 14-cyclohexyl-7-[methyl(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate
• CAS NO: 886041-81-2
• Molecular Weight: 515.696
• Mol File: 886041-81-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 14-cyclohexyl-7-[methyl(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 14-cyclohexyl-7-[methyl(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(886041-81-2)
• EPA Substance Registry System: methyl 14-cyclohexyl-7-[methyl(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(886041-81-2)

Safety Data

• Hazardous Substances Data: 886041-81-2(Hazardous Substances Data)

Upstream product

• 494799-19-8 methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate 
• 89466-08-0 2-hydroxyphenyl boronic acid 
• 886041-55-0 methyl 14-cyclohexyl-7-oxo-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 
• 886041-54-9 methyl (7S)-14-cyclohexyl-7-hydroxy-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 
• 886041-53-8 3-cyclohexyl-2-{2-[(2S)-oxiran-2-ylmethoxy]phenyl}-1H-indole-6-carboxylic acid methyl ester 
• 863578-50-1 3-cyclohexyl-2-(2-hydroxy-phenyl)-1H-indole-6-carboxylic acid methyl ester 
• 50-00-0 formaldehyd 
• 886041-80-1 methyl 14-cyclohexyl-7-[(2-pyrrolidin-1-ylethyl)amino]-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 

Relevant articles and documents

Discovery of (7 R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6 H -indolo[1,2- e ][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase

Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication of viral genome and has been a prime target for drug discovery eff