886209-46-7

Basic information

• Product Name: 4-(1-fluoro-cyclooct-2-ynylmethyl)benzoic acid
• Synonyms: 4-(1-fluoro-cyclooct-2-ynylmethyl)benzoic acid
• CAS NO: 886209-46-7
• Molecular Weight: 260.308
• Mol File: 886209-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1-fluoro-cyclooct-2-ynylmethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-fluoro-cyclooct-2-ynylmethyl)benzoic acid(886209-46-7)
• EPA Substance Registry System: 4-(1-fluoro-cyclooct-2-ynylmethyl)benzoic acid(886209-46-7)

Safety Data

• Hazardous Substances Data: 886209-46-7(Hazardous Substances Data)

Upstream product

• 1755-14-2 α-fluorocycloctanone 
• 502-49-8 cycloactanone 
• 50338-42-6 (cyclooct-1-enyloxy)-trimethylsilane 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 

Downstream Products

• 1363182-02-8 MOFO-N,N'-dimethyl-1,6-hexanediamine 
• 1048651-95-1 C₃₄H₃₈F₂N₂O₂ 

Relevant articles and documents

Compositions and methods for modification of biomolecules

The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).