886362-19-2

Basic information

• Product Name: 3-(1'-AMINOETHYL)-1-N-BOC-ANILINE
• Synonyms: Carbamic acid, [3-(1-aminoethyl)phenyl]-, 1,1-dimethylethyl ester (9CI);tert-Butyl N-[3-(1-aminoethyl)phenyl]carbamate;1-(3-(BOC-AMINO)-PHENYL)-ETHYLAMINE
• CAS NO: 886362-19-2
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.313
• Mol File: 886362-19-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 303.6 °C at 760 mmHg
• Flash Point: 137.4 °C
• Appearance: /
• Density: 1.095 g/cm³
• Vapor Pressure: 0.000923mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 3-(1'-AMINOETHYL)-1-N-BOC-ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1'-AMINOETHYL)-1-N-BOC-ANILINE(886362-19-2)
• EPA Substance Registry System: 3-(1'-AMINOETHYL)-1-N-BOC-ANILINE(886362-19-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 886362-19-2(Hazardous Substances Data)

Usage

General Description

3-(1'-aminoethyl)-1-N-BOC-aniline is a chemical compound with the molecular formula C14H23N3O2. It is an aromatic amine with a BOC-protected primary amine group and a terminal aminoethyl group, making it a useful building block for the synthesis of complex organic compounds. The BOC-protected amine group provides a means for selective functionalization, while the aminoethyl group can participate in chemical reactions such as cross-coupling and reductive amination. 3-(1'-AMINOETHYL)-1-N-BOC-ANILINE has potential applications in the pharmaceutical industry for the synthesis of drug molecules, as well as in the field of organic synthesis for the preparation of diverse chemical products.

InChI:InChI=1/C13H20N2O2/c1-9(14)10-6-5-7-11(8-10)15-12(16)17-13(2,3)4/h5-9H,14H2,1-4H3,(H,15,16)

Upstream product

• 129725-48-0 α-(3-aminophenyl)ethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

A method for the selective protection of aromatic amines in the presence of aliphatic amines

A simple and efficient procedure has been developed for the regioselective protection of aromatic amines in the presence of aliphatic amines. The method is general for the preparation of mono-N-Boc, -N-Cbz, -N-Fmoc or -N-Alloc aromatic amines in high yield without affecting the aliphatic amines. This approach is applicable to substituted (aminoalkyl)aniline compounds with different functionalities and was employed to supply gram quantities of the protected aniline product. Georg Thieme Verlag Stuttgart · New York.