886362-62-5 Usage
General Description
4-(3-Bromo-phenyl)-1-N-BOC-piperidine is a chemical compound with the molecular formula C16H23BrN2O2. It is a piperidine derivative with a bromo-phenyl group and a BOC (tert-butoxycarbonyl) protecting group attached to the nitrogen atom. 4-(3-BROMO-PHENYL)-1-N-BOC-PIPERIDINE is often used in organic synthesis and pharmaceutical research as a building block or intermediate. It has potential applications in the development of new drugs or as a precursor for the synthesis of other bioactive molecules. Overall, 4-(3-Bromo-phenyl)-1-N-BOC-piperidine is a valuable and versatile chemical compound with various potential uses in the field of chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 886362-62-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,3,6 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 886362-62:
(8*8)+(7*8)+(6*6)+(5*3)+(4*6)+(3*2)+(2*6)+(1*2)=215
215 % 10 = 5
So 886362-62-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H22BrNO2/c1-16(2,3)20-15(19)18-9-7-12(8-10-18)13-5-4-6-14(17)11-13/h4-6,11-12H,7-10H2,1-3H3
886362-62-5Relevant articles and documents
Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors
Bayliss, Tracy,Robinson, David A.,Smith, Victoria C.,Brand, Stephen,McElroy, Stuart P.,Torrie, Leah S.,Mpamhanga, Chido,Norval, Suzanne,Stojanovski, Laste,Brenk, Ruth,Frearson, Julie A.,Read, Kevin D.,Gilbert, Ian H.,Wyatt, Paul G.
supporting information, p. 9790 - 9806 (2017/12/26)
N-Myristoyltransferase (NMT) represents a promising drug target within the parasitic protozoa Trypanosoma brucei (T. brucei), the causative agent for human African trypanosomiasis (HAT) or sleeping sickness. We have previously validated T. brucei NMT as a promising druggable target for the treatment of HAT in both stages 1 and 2 of the disease. We report on the use of the previously reported DDD85646 (1) as a starting point for the design of a class of potent, brain penetrant inhibitors of T. brucei NMT.
