886364-86-9

Basic information

• Product Name: 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE
• Synonyms: 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE;5-BroMo-2-cyano-4-Methylpyridine;5-BroMo-4-Methylpicolinonitrile;5-Bromo-2-cyano-4-methylpyridine, 5-Bromo-4-methylpicolinonitrile;5-bromo-4-methyl-2-Pyridinecarbonitrile
• CAS NO: 886364-86-9
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.032
• Product Categories: Heterocycle-Pyridine series
• Mol File: 886364-86-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 293.289 °C at 760 mmHg
• Flash Point: 131.177 °C
• Appearance: /
• Density: 1.613 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.02±0.18(Predicted)
• CAS DataBase Reference: 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE(886364-86-9)
• EPA Substance Registry System: 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE(886364-86-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN2811
• Hazardous Substances Data: 886364-86-9(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-methyl-pyridine-2-carbonitrile is a chemical compound with the molecular formula C7H5BrN2. It is a pyridine derivative that contains a bromine atom and a methyl group. 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE is commonly used in organic synthesis as a building block for pharmaceuticals, agrochemicals, and materials science. It is also known for its application in the development of various drugs and biologically active compounds. Additionally, 5-Bromo-4-methyl-pyridine-2-carbonitrile has been studied for its potential anti-inflammatory and antiviral properties, making it an important compound in the field of medicinal chemistry.

Upstream product

• 98198-48-2 2-amino-5-bromo-4-methylpyridine 

Downstream Products

• 1070889-97-2 4-chloro-3-(6-cyano-4-methyl-pyridin-3-yl)-N-[2-(3-hydroxy-propoxy)-phenyl]-N-methyl-benzamide 
• 1070890-06-0 3-(2-{[4-chloro-3-(6-cyano-4-methyl-pyridin-3-yl)-benzoyl]-methyl-amino}-phenoxy)-propionic acid 
• 1256792-51-4 5-hydroxy-4-methylpyridine-2-carbonitrile 
• 1070973-10-2 3-[5-chloro-4-(6-cyano-4-methyl-pyridin-3-yl)-2-(2,3,4,5-tetrahydro-benzo[b]azepine-1-sulfonyl)-phenoxy]-propionic acid 
• 1070973-11-3 5-[2-chloro-4-(3-hydroxy-propoxy)-5-(2,3,4,5-tetrahydro-benzo[b]azepine-1-sulfonyl)-phenyl]-4-methyl-pyridine-2-carbonitrile 
• 1413285-70-7 2-[[6-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-4-methyl-3-pyridyl]sulfanyl]acetic acid 
• 1413285-69-4 ethyl 2-[[6-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-4-methyl-3-pyridyl]sulfanyl]acetate 
• 1309959-26-9 5-bromo-2-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-4-methyl-pyridine 
• 1413285-68-3 1-(5-bromo-4-methyl-2-pyridyl)ethanone 
• 1070973-08-8 5-[2-chloro-4-hydroxy-5-(2,3,4,5-tetrahydro-benzo[b]azepine-1-sulfonyl)-phenyl]-4-methyl-pyridine-2-carbonitrile 
• 1070889-90-5 4-chloro-3-(6-cyano-4-methyl-pyridin-3-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide 

Relevant articles and documents

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.