88639-49-0

Basic information

• Product Name: Benzoic acid, 4-Methyl-, 2,2,2-trifluoroethyl ester
• Synonyms: Benzoic acid, 4-Methyl-, 2,2,2-trifluoroethyl ester
• CAS NO: 88639-49-0
• Molecular Formula: C₁₀H₉F₃O₂
• Molecular Weight: 218.1724696
• Mol File: 88639-49-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-Methyl-, 2,2,2-trifluoroethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-Methyl-, 2,2,2-trifluoroethyl ester(88639-49-0)
• EPA Substance Registry System: Benzoic acid, 4-Methyl-, 2,2,2-trifluoroethyl ester(88639-49-0)

Safety Data

• Hazardous Substances Data: 88639-49-0(Hazardous Substances Data)

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 99-94-5 p-Toluic acid 
• 874-60-2 4-methyl-benzoyl chloride 
• 64-17-5 ethanol 
• 77253-67-9 trifluoroethanol-d₃ 
• 589-18-4 4-Methylbenzyl alcohol 

Downstream Products

• 75-89-8 2,2,2-trifluoroethanol 
• 937-21-3 4-methylperbenzoic acid 
• 99-94-5 p-Toluic acid 

Relevant articles and documents

Construction of Esters through Sulfuryl Fluoride (SO 2 F 2) Mediated Dehydrative Coupling of Carboxylic Acids with Alcohols at Room Temperature

A facile method for the construction of esters through dehydrative coupling of carboxylic acids with alcohols is developed. The reactions are mediated by sulfuryl fluoride (SO 2 F 2) at room temperature and proceed with high efficiency. The method has several advantages including broad substrate scope, mild conditions, excellent functional group compatibility and affords high yields, even on gram scale.

METHOD FOR PRODUCING DEUTERATED PERFLUOROALYKYL METHANOL

PROBLEM TO BE SOLVED: To provide a method for safely and efficiently producing a deuterated perfluoroalykyl methanol. SOLUTION: This method for producing the deuterated perfluoroalykyl methanol expressed by general formula (I): RfCD2O-A (Rf is a perfluoroalkyl; and A is D or H) comprises reducing an perfluorcarboxylic acid anhydride expressed by general formula (II): (RfCO)2O by using deuterium in the presence of a transition metal catalyst.

Facile conversion of alcohols to the corresponding 2,2,2-trifluoroethyl esters with molecular iodine and potassium carbonate in 2,2,2-trifluoroethanol

A simple, effective, and high-yield procedure for the oxidative conversion of primary alcohols to the corresponding 2,2,2-trifluoroethyl esters, with molecular iodine and potassium carbonate in 2,2,2-trifluoroethanol, was studied.