886733-97-7

Basic information

• Product Name: 3,5-Hexadienoic acid, 2,4-dimethyl-2-[(3-oxopropyl)thio]-, phenylmethyl ester, (2R,3E)-
• CAS NO: 886733-97-7
• Molecular Formula: C18H22O3S
• Molecular Weight: 318.437
• Mol File: 886733-97-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-Hexadienoic acid, 2,4-dimethyl-2-[(3-oxopropyl)thio]-, phenylmethyl ester, (2R,3E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Hexadienoic acid, 2,4-dimethyl-2-[(3-oxopropyl)thio]-, phenylmethyl ester, (2R,3E)-(886733-97-7)
• EPA Substance Registry System: 3,5-Hexadienoic acid, 2,4-dimethyl-2-[(3-oxopropyl)thio]-, phenylmethyl ester, (2R,3E)-(886733-97-7)

Safety Data

• Hazardous Substances Data: 886733-97-7(Hazardous Substances Data)

Upstream product

• 241806-94-0 (2E,4E)-2,4-dimethylhexa-2,4-dienoic acid 
• 62332-68-7 ethyl (2E,4E)-2,4-dimethylhexa-2,4-dienoate 
• 497-03-0 2-methylbut-2-enal 
• 886733-91-1 (R)-4-benzyl-3-[(R,E)-2-(3,3-dimethoxypropylthio)-2,4-dimethylhexa-3,5-dienoyl]oxazolidin-2-one 
• 886733-93-3 (R)-4-benzyl-3-[(2E,4E)-2,4-dimethylhexa-2,4-dienoyl]oxazolidin-2-one 
• 886733-96-6 (R,E)-benzyl 2-(3,3-dimethoxypropylthio)-2,4-dimethylhexa-3,5-dienoate 

Downstream Products

• 886733-90-0 (R,E)-benzyl 2,4-dimethyl-2-(acetylthio)hexa-3,5-dienoate 
• 886733-89-7 (R,E)-benzyl 2,4-dimethyl-2-(propionylthio)hexa-3,5-dienoate 
• 82079-32-1 (+)-thiolactomycin 
• 1143584-04-6 (R,E)-benzyl 2,4-dimethyl-2-[(E,Z)-3-(propionyloxy)prop-2-enylthio]hexa-3,5-dienoate 

Relevant articles and documents

Efficient synthesis of enantiomeric pairs of thiolactomycin and its 3-demethyl derivative

Starting with commercially available tiglic aldehyde, the title synthesis was achieved by employing deconjugative asymmetric α-sulfenylation of the chiral 3-(α,β,γ,δ-unsaturated acyl)-2-oxazolidinone with a methanethiosulfonate as a key step.