886766-28-5

Basic information

• Product Name: 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER;4,7-Diazaspiro[2.5]octane-7-carboxylic acid, 1,1-dimethylethyl ester;4,7-Diaza-spiro[2.5]octane-7-carboxylic acid tert-butyl ester hcl;tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate hydrochloride;7-Boc-4,7-diaza-spiro[2.5]octane
• CAS NO: 886766-28-5
• Molecular Formula: C₁₁H₂₀N₂O₂
• Molecular Weight: 212.2887
• Mol File: 886766-28-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 301.3 ºC at 760 mmHg
• Flash Point: 136ºC
• Appearance: /
• Density: 1.1 g/cm³
• Vapor Pressure: 0.00106mmHg at 25°C
• Refractive Index: 1.521
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.54±0.20(Predicted)
• CAS DataBase Reference: 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER(886766-28-5)
• EPA Substance Registry System: 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER(886766-28-5)

Safety Data

• Hazardous Substances Data: 886766-28-5(Hazardous Substances Data)

Usage

General Description

4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER is a chemical compound with the molecular formula C11H21NO3. It is a tert-butyl ester derivative of 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID. 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER is often used in organic synthesis and as a building block in the production of pharmaceuticals and other fine chemicals. It has a spirocyclic structure with a nitrogen-containing ring, making it useful for its unique properties in various chemical reactions and processes. 4,7-DIAZA-SPIRO[2.5]OCTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER may also have potential applications in the development of new materials due to its specific chemical structure and reactivity.

InChI:InChI=1/C11H20N2O2/c1-10(2,3)15-9(14)13-7-6-12-11(8-13)4-5-11/h12H,4-8H2,1-3H3

Upstream product

• 76003-29-7 4-(t-butyloxycarbonyl)piperazin-2-one 
• 1261358-79-5 tert-butyl 4-benzyl-4,7-diazaspiro[2.5]octane-7-carboxylate 
• 78551-60-7 1-benzyl-4-(tert-butyloxycarbonyl)piperazin-2-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 99214-52-5 4,7-diazaspiro[2.5]octane 

Downstream Products

• 1254981-66-2 4-phenyl-4,7-diaza-spiro[2.5]octane-7-carboxylic acid tert-butyl ester 

Relevant articles and documents

NOVEL SUBSTITUTED PIPERAZINE AMIDE COMPOUNDS AS INDOLEAMINE 2, 3-DIOXYGENASE (IDO) INHIBITORS

Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROY2.5¨OCTANE RING STRUCTURE

There is provided a novel compound that inhibits the interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. The present invention provides an imidazothiazole derivative represented by the following formula (1) having various substituents that inhibits the interaction between Mdm2 protein and p53 protein and exhibits anti-tumor activity: wherein R1 R2, R3, R4, R5, Ar1, and Ar2 in formula (1) each have the same meanings as defined in the specification.