886841-69-6Relevant articles and documents
Synthesis of some floctafenine derivatives of expected anti-inflammatory/ analgesic activity
Hegazy, Gehan Hegazy,Taher, Azza,El-Zaher, Asmaa Ahmed
, p. 378 - 384 (2005)
New derivatives related to floctafenine were synthesized and representative examples were screened for their anti-inflammatory and analgesic activities. All compounds tested were found to exhibit anti-inflammatory and analgesic activities and some were more potent than the references, floctafenine and indomethacin, in carragenan-induced rat's paw edema. None of the tested compounds showed an ulcerogenic effect on the p-benzoquinone-induced writhing test in mice.