886853-78-7

Basic information

• Product Name: 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine
• Synonyms: 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine
• CAS NO: 886853-78-7
• Molecular Weight: 383.082
• Mol File: 886853-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine(886853-78-7)
• EPA Substance Registry System: 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine(886853-78-7)

Safety Data

• Hazardous Substances Data: 886853-78-7(Hazardous Substances Data)

Downstream Products

• 149913-92-8 6-benzyloxy-2-phenyl-1H-indole 
• 1146543-27-2 1-[5-benzyloxy-2-(2,2-dibromo-vinyl)-phenyl]-1H-pyrrole 
• 1240045-36-6 6-(benzyloxy)-2-bromo-1H-indole 
• 1067249-40-4 5-(benzyloxy)-2-(2,2-dibromovinyl)-N-(3-thienylmethyl)aniline 

Relevant articles and documents

A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles

(Chemical Equation Presented) A highly efficient method of indole synthesis using gem-dihalovinylaniline substrates and an organoboron reagent was developed via a Pd-catalyzed tandem intramolecular amination and an intermolecular Suzuki coupling. Aryl, alkenyl, and alkyl boron reagents are all successfully employed, making for a versatile modular approach. The reaction tolerates a variety of substitution patterns on the aniline leading to indoles with group at C2-C7. The orthogonal approach of the sequential copper- and palladium-mediated synthesis of 1,2-diarylindoles exploited the wide availability of diverse organoboron reagents.