88740-52-7

Basic information

• Product Name: 1H-Imidazolium, 1-acetyl-3-[2-oxo-2-[4-(2-phenylethyl)phenyl]ethyl]-, bromide
• CAS NO: 88740-52-7
• Molecular Formula: C21H21N2O2.Br
• Molecular Weight: 413.314
• Mol File: 88740-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Imidazolium, 1-acetyl-3-[2-oxo-2-[4-(2-phenylethyl)phenyl]ethyl]-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazolium, 1-acetyl-3-[2-oxo-2-[4-(2-phenylethyl)phenyl]ethyl]-, bromide(88740-52-7)
• EPA Substance Registry System: 1H-Imidazolium, 1-acetyl-3-[2-oxo-2-[4-(2-phenylethyl)phenyl]ethyl]-, bromide(88740-52-7)

Safety Data

• Hazardous Substances Data: 88740-52-7(Hazardous Substances Data)

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 28179-32-0 2-bromo-1-[4-(2-phenylethyl)phenyl]ethanone 

Downstream Products

• 73931-88-1 2-(1H-imidazol-1-yl)-1-[4-(2-phenylethyl)phenyl]ethan-1-one 

Relevant articles and documents

An improved and convenient procedure for the synthesis of 1-substituted imidazoles

1-Protected imidazoles, such as 1-acetyl- and 1-benzoylimidazoles, react with various halides, such as benzyl, allyl, α-keto, and alkyl halides, to give 1-protected-3-substituted imidazolium salts in high yields. The resultant imidazolium salts are easily deprotected by treatment with water or alcohols to give the corresponding 1-substituted imidazoles in excellent yields. In this reaction the yields of 1-substituted imidazoles vary with the kinds of halides used and/or with the protecting groups, and the yields increase in the following order: benzyl halides≥allyl halides~α-keto halides>alkyl halides, and acetyl≥benzoyl>ethoxycarbonyl>diethoxymethyl>trimethylsilyl>tosyl.