887587-50-0 Usage
Description
6-Bromo-4-chloro-quinoline-2-carboxylic acid methyl ester is a chemical compound with the molecular formula C11H7BrClNO2. It is a methyl ester derivative of 6-bromo-4-chloro-quinoline-2-carboxylic acid and is commonly used as an intermediate in the synthesis of pharmaceutical compounds. This quinoline derivative is known for its diverse biological activities, including antimicrobial, anti-inflammatory, and antimalarial properties. The methyl ester form enhances its stability and ease of handling in laboratory settings, making it a valuable building block for the synthesis of more complex molecules with potential pharmacological applications.
Uses
Used in Pharmaceutical Industry:
6-Bromo-4-chloro-quinoline-2-carboxylic acid methyl ester is used as an intermediate in the synthesis of pharmaceutical compounds for its diverse biological activities. Its antimicrobial, anti-inflammatory, and antimalarial properties make it a promising candidate for the development of new drugs to treat various diseases and conditions.
Used in Research and Development:
In the field of research and development, 6-bromo-4-chloro-quinoline-2-carboxylic acid methyl ester serves as a building block for the synthesis of more complex molecules with potential pharmacological applications. Its stability and ease of handling make it an ideal candidate for use in laboratory settings to explore new drug candidates and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 887587-50-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,8 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 887587-50:
(8*8)+(7*8)+(6*7)+(5*5)+(4*8)+(3*7)+(2*5)+(1*0)=250
250 % 10 = 0
So 887587-50-0 is a valid CAS Registry Number.
887587-50-0Relevant articles and documents
Synthesis of quinoline thioethers as novel small molecule enhancers of monoclonal antibody production in mammalian cell culture
Kazi, Shahid A.,Kelso, Geoffrey F.,Harris, Simon,Boysen, Reinhard I.,Chowdhury, Jamil,Hearn, Milton
scheme or table, p. 9461 - 9467 (2011/01/12)
A small library of novel quinoline derivatives containing different thioether substituents at position 4 have been synthesized and screened in murine hybridoma cell culture for their ability to enhance monoclonal antibody (mAb) production. From this set of compounds, four compounds have been discovered that enhanced immunoglobulin G (IgG) titer over negative control cultures due to an increase in specific productivity. These results demonstrate the utility of using organic synthesis and parallel ligand screening methods to discover novel cell culture additives that may be useful for increasing mAb yield in industrial biomanufacturing processes.
