887590-46-7 Usage
Description
(2,2-DIMETHYL-PROPYL)-(3-TRIFLUOROMETHYL-PHENYL)-AMINE, also known as 2,2-dimethylpropyl-(3-trifluoromethylphenyl)amine, is an organic compound with the molecular formula C14H18F3N. It is a substituted aniline derivative that is commonly used in the pharmaceutical and agrochemical industries. (2,2-DIMETHYL-PROPYL)-(3-TRIFLUOROMETHYL-PHENYL)-AMINE is known for its versatile role as a building block in the synthesis of various biologically active compounds, including pharmaceutical drugs and pesticides. Due to its potential toxic and hazardous nature, it is important to handle this chemical with care and in accordance with proper safety protocols.
Uses
Used in Pharmaceutical Industry:
(2,2-DIMETHYL-PROPYL)-(3-TRIFLUOROMETHYL-PHENYL)-AMINE is used as a building block for the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new and effective medications with various therapeutic applications.
Used in Agrochemical Industry:
(2,2-DIMETHYL-PROPYL)-(3-TRIFLUOROMETHYL-PHENYL)-AMINE is used as a building block for the synthesis of pesticides. Its properties make it suitable for the creation of effective pest control agents that can help protect crops and maintain agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 887590-46-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,9 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 887590-46:
(8*8)+(7*8)+(6*7)+(5*5)+(4*9)+(3*0)+(2*4)+(1*6)=237
237 % 10 = 7
So 887590-46-7 is a valid CAS Registry Number.
887590-46-7Relevant articles and documents
Reductive Amination by Photoredox Catalysis and Polarity-Matched Hydrogen Atom Transfer
Guo, Xingwei,Wenger, Oliver S.
supporting information, p. 2469 - 2473 (2018/01/27)
The excitation of a RuII photosensitizer in the presence of ascorbic acid leads to the reduction of iminium ions to electron-rich α-aminoalkyl radical intermediates, which are rapidly converted into reductive amination products by thiol-mediated hydrogen atom transfer (HAT). As a result, the reductive amination of carbonyl compounds with amines by photoredox catalysis proceeds in good to excellent yields and with broad substrate scope and good functional group tolerance. The three key features of this work are 1) the rapid interception of electron-rich α-aminoalkyl radical intermediates by polarity-matched HAT in a photoredox reaction, 2) the method of reductive amination by photoredox catalysis itself, and 3) the application of this new method for temporally and spatially controlled reactions on a solid support, as demonstrated by the attachment of a fluorescent dye on an activated cellulose support by photoredox-catalyzed reductive amination.
