88775-45-5

Basic information

• Product Name: (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one
• Synonyms: 2-propen-1-one, 1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)-, (2E)-; 2-Propen-1-one, 1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)-, (E)-
• CAS NO: 88775-45-5
• Molecular Formula: C₁₈H₁₆O₅
• Molecular Weight: 312.3166
• Mol File: 88775-45-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 495.5°C at 760 mmHg
• Flash Point: 220.5°C
• Density: 1.254g/cm³
• Vapor Pressure: 5.87E-10mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one(88775-45-5)
• EPA Substance Registry System: (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one(88775-45-5)

Safety Data

• Hazardous Substances Data: 88775-45-5(Hazardous Substances Data)

Usage

Description

(2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is a complex organic compound that belongs to the class of prop-2-en-1-ones, which are ketones. This molecule features a benzodioxol ring and a dimethoxyphenyl ring, contributing to its unique chemical properties and potential biological activities. It is widely recognized for its use in pharmaceutical research and drug development, making it a valuable asset in the fields of medicine, chemistry, and biotechnology.

Uses

Used in Pharmaceutical Research and Drug Development:
(2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and chemical properties make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one serves as a valuable building block for the design and synthesis of novel bioactive molecules. Its presence in a compound can potentially enhance the molecule's pharmacological properties, such as potency, selectivity, and bioavailability.
Used in Biotechnology:
(2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one may also find applications in biotechnology, where it can be employed as a component in the development of new biological tools and technologies. Its potential biological activities could be harnessed to create innovative solutions in areas such as diagnostics, therapeutics, and drug delivery systems.
Used in Chemical Synthesis:
As an organic compound with a complex molecular structure, (2E)-1-(1,3-benzodioxol-5-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one is also used in chemical synthesis for the preparation of various organic compounds. Its versatility and reactivity make it a valuable resource in the synthesis of specialty chemicals and materials.

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 6329-73-3 1-benzo[1,3]dioxol-5-yl-ethanol 
• 120-57-0 piperonal 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 

Downstream Products

• 1575481-03-6 3-(benzo[d][1,3]dioxol-5-yl)-5-(3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazole 
• 1252015-06-7 ethyl 4-(1,3-benzodioxol-5-yl)-6-(3,4-dimethoxyphenyl)-2-oxocyclohex-3-ene-1-carboxylate 
• 80816-90-6 4-(3,4-dimethoxyphenyl)-6,7-methylenedioxy-3,4-dihydronaphthalen-1(2H)-one 
• 82245-79-2 1-(3,4-dimethoxyphenyl)-3-ethoxycarbonyl-6,7-methylenedioxynaphthalene 
• 76934-63-9 4-(3,4-dimethoxyphenyl)-3-ethoxycarbonyl-6,7-methylenedioxy-3,4-dihydronaphthalene-1(2H)-one 
• 105594-89-6 2-(3,4-dimethoxyphenyl)-6,7-methylenedioxy-1-(N-methylformamido)naphthalene 
• 105594-81-8 cis-2-(3,4-dimethoxyphenyl)-N-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydro-1-naphthylamine 
• 88114-55-0 2-(3,4-dimethoxyphenyl)-6-hydroxy-7-methoxy-1-(N-methylformamido)naphthalene 
• 41303-46-2 2-(3,4-dimethoxyphenyl)-6,7-methylenedioxy-3,4-dihydronaphthalen-1(2H)-one 
• 52259-64-0 fagaronine 
• 13063-04-2 nitidine chloride 
• 80816-88-2 Benzo[1,3]dioxol-5-yl-[2-(3,4-dimethoxy-phenyl)-cyclopropyl]-methanone 
• 76959-99-4 ethyl 3-(3,4-dimethoxyphenyl)-2-(3,4-methylenedioxybenzoyl)cyclopropane-1-carboxylate 
• 54022-58-1 2-(3,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxobutyronitrile 

Relevant articles and documents

Synthesis and characterization of novel benzo[d][1,3]dioxole gathered pyrazole derivatives and their antimicrobial evaluation

Benzo[d][1,3]dioxole gathered pyrazole derivatives (4a-i) were synthesized by the reaction of chalcones with phenyl hydrazine in presence of absolute alcohol as a solvent. Chalcones were prepared by the Claisen-Schmidt reaction between 1-(benzo[d][1,3]dioxol-5-yl)ethanone (2) and substituted aromatic aldehydes. The synthesized compounds were characterized by spectral and elemental analysis data. Furthermore, Benzo[ d][1,3]dioxole gathered pyrazole derivatives (4a-i) were evaluated for their in vitro antimicrobial activity. Among the newly synthesized compounds 4a, 4c, 4 g and 4 h showed the excellent antifungal activity and as well as 4a and 4d showed the excellent antibacterial activity when compared to other compounds. Springer Science+Business Media 2014.

Studies on the chemical constituents of rutaceous plants. XLIX. Development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (1). Preparation of various 2,4-bisaryl-4-oxobutyronitriles and 2,4-bisaryl-4-oxobutyramides

For the sake of establishment of a versatile synthetic method for benzo[c]phenanthridine alkaloids, improvement of the Robinson synthetic method was examined. Thirteen chalcones (7a-m) were prepared by condensation of two acetophenone derivatives (15 and 16) with eleven benzaldehyde derivatives (19a-k) as fundamental starting materials. Hydrocyanation of these chalcones (7a-1) except one (7m) gave the corresponding 2,4-bisaryl-4-oxobutyronitriles (8a-1). Eleven 2,4-bisaryl-4-oxobutyramides (9a-k) were also prepared.