888072-26-2Relevant articles and documents
Serendipitous discovery of novel imidazolopyrazole scaffold as selective androgen receptor modulators
Zhang, Xuqing,Li, Xiaojie,Allan, George F.,Sbriscia, Tifanie,Linton, Olivia,Lundeen, Scott G.,Sui, Zhihua
, p. 439 - 443 (2007/10/03)
A novel imidazolopyrazole derivative has been fortuitously discovered as potent selective androgen receptor modulator with in vivo efficacy.
Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators
Zhang, Xuqing,Allan, George F.,Sbriscia, Tifanie,Linton, Olivia,Lundeen, Scott G.,Sui, Zhihua
, p. 5763 - 5766 (2008/12/22)
A novel series of hydantoin derivatives were identified by in vivo studies as tissue selective androgen receptor modulators. SAR around this series revealed that the function of the ligand could be altered by minor structural modification.