88854-01-7Relevant articles and documents
PREPARATION OF 2'(3')-O-Acyl-pCpA DERIVATIVES AS SUBSTRATES FOR T4 RNA LIGASE-MEDIATED "CHEMICAL AMINOACILATION"
Heckler, T.G.,Chang, L.H.,Zama, Y.,Naka, T.,Hecht, S.M.
, p. 87 - 94 (2007/10/02)
The synthesis of 2'(3')-O-(amino)acyl-pCpA derivatives is described and the products are characterized chemically and as substrates for T4 RNA ligase in the presence of E.coli tRNAPhe-COH.The modified (N-acetylamino)acyl-tRNA's so derived are characterized by their chromatographic and biochemical properties, and by their ability to act as P-site t-RNA donors in the peptidyltransferase reaction.