88930-15-8

Basic information

• Product Name: (10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol
• Synonyms: (10α,24R)-3β,11α,24,25-Tetrahydroxy-9β-methyl-19-norlanosta-5-ene;(10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol;(24R)-Cucurbit-5-ene-3β,11α,24,25-tetrol;Mogrol
• CAS NO: 88930-15-8
• Molecular Formula: C30H52O4
• Molecular Weight: 476.73148
• Mol File: 88930-15-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 595.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• PKA: 14.67±0.29(Predicted)
• CAS DataBase Reference: (10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol(CAS DataBase Reference)
• NIST Chemistry Reference: (10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol(88930-15-8)
• EPA Substance Registry System: (10α,24R)-9β-Methyl-19-norlanosta-5-ene-3β,11α,24,25-tetrol(88930-15-8)

Safety Data

• Hazardous Substances Data: 88930-15-8(Hazardous Substances Data)

Usage

Appearance

Constit. of Cucurbita foeridissimia (buffalo gourd).Amorph. powder.

Biochem/physiol Actions

Mogrol is an aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities. It induces apoptosis in K562 leukemia cells through suppression of ERK1/2 and STAT3 pathways. Mogrol appears to ameliorate the memory impairment caused by Aβ1-42 in mice. Mogrol increases AMPK activity in hepatocytes and suppresses adipocyte differentiation in 3T3-L1 cells.