88971-40-8 Usage
Description
BOC-L-DPA(BOC)-OH, also known as t-butoxycarbonyl-L-phenylalanine(BOC)-OH, is a white crystalline solid that is an amino acid derivative. It is commonly used in organic synthesis and peptide chemistry as a building block for the preparation of various peptides and peptidomimetics. The BOC group serves as a protective group for the amino acid, allowing for selective deprotection and functionalization of specific functional groups during peptide synthesis.
Uses
Used in Medicinal Chemistry and Drug Discovery:
BOC-L-DPA(BOC)-OH is used as a building block for the development of peptide-based therapeutics and pharmaceuticals. Its protective BOC group allows for selective deprotection and functionalization of specific functional groups during peptide synthesis, making it a valuable component in the creation of novel peptide-based drugs.
Used in Organic Synthesis:
BOC-L-DPA(BOC)-OH is used as a key intermediate in the synthesis of complex organic molecules. Its versatility as an amino acid derivative makes it a useful component in the development of new chemical entities with potential applications in various industries.
Used in Peptide Chemistry:
BOC-L-DPA(BOC)-OH is used as a component in the synthesis of peptidomimetics, which are compounds that mimic the structure and function of peptides. These peptidomimetics have potential applications in the development of new drugs and therapeutic agents, particularly in the treatment of diseases that are difficult to target with traditional small molecule drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 88971-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,7 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 88971-40:
(7*8)+(6*8)+(5*9)+(4*7)+(3*1)+(2*4)+(1*0)=188
188 % 10 = 8
So 88971-40-8 is a valid CAS Registry Number.
88971-40-8Relevant articles and documents
A template-directed synthetic approach to halogen-bridged mixed-valence platinum complexes on artificial peptides in solution
Tanaka, Kentaro,Kaneko, Kenji,Watanabe, Yusuke,Shionoya, Mitsuhiko
, p. 5369 - 5371 (2007)
A template-directed synthetic approach to halogen-bridged mixed-valence platinum complexes has been performed in organic media using, for instance, a synthetic peptide bearing two bis(ethylenediamine)-based Pt(iv) complexes with two axial bromide anionic ligands, [1a(Pt(iv)Br2(en)) 2](RSO3)4, and a [Pt(ii)(en) 2](RSO3)2 complex (R = (C12H 25OCH2)2CHO(CH2)3-). The Royal Society of Chemistry.
Synthesis and nematicidal activity of piperazinedione derivatives based on the natural product Barettin
Sun, Haiyang,Li, Hui,Wang, Jiayi,Song, Gonghua
, p. 977 - 980 (2017/11/16)
Nematodes are serious constraints of crop production worldwide. However, the traditional nematicides suffer from the side-effects, including environmental and human toxicity. Herein, more than 70 novel piperazinedione derivatives based on the natural product Barettin were synthesized and evaluated against the root-knot nematode Meloidogyne incognita (M. incognita). While most of synthesized compounds exhibited certain nematicidal activity at high concentration, the best one showed a nematicidal activity of 75% at 2.4 μmol/L.
Relationship between Taste and Structure of O-Aminoacyl Sugars Containing Basic Amino Acids
Tamura, Masahiro,Nakamura, Kozo,Kinomura, Keisuke,Okai, Hideo
, p. 20 - 23 (2007/10/02)
To study the relationship between taste and structure of O-aminoacyl sugars, a number of O-aminoacyl sugars containing basic amino acids were prepared.Taste quality of O-aminoacyl sugars was dependent on the side chain length of basic amino acids that were introduced into sugars.O-Aminoacyl sugars had an excellent sodium ion diet effect that could reduce sodium ion intake to 10 percent.