89019-83-0

Basic information

• Product Name: Ethanone, 1-(2,4-dihydroxyphenyl)-2-(3-methoxyphenyl)-
• CAS NO: 89019-83-0
• Molecular Formula: C15H14O4
• Molecular Weight: 258.274
• Mol File: 89019-83-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2,4-dihydroxyphenyl)-2-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,4-dihydroxyphenyl)-2-(3-methoxyphenyl)-(89019-83-0)
• EPA Substance Registry System: Ethanone, 1-(2,4-dihydroxyphenyl)-2-(3-methoxyphenyl)-(89019-83-0)

Safety Data

• Hazardous Substances Data: 89019-83-0(Hazardous Substances Data)

Upstream product

• 1798-09-0 m-methoxyphenylacetic acid 
• 108-46-3 recorcinol 

Downstream Products

• 877177-87-2 7-Methoxy-3-(3-methoxy-phenyl)-chromen-4-one 
• 139256-06-7 7-hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one 
• 1239488-85-7 C₂₁H₁₈ClNO₃ 

Relevant articles and documents

Enantioselective Synthesis of Isoflavanones and Pterocarpans through a RuII-Catalyzed ATH-DKR of Isoflavones

Noyori-Ikariya RuII complexes promoted the one-pot C=C/C=O bonds reduction of isoflavones using sodium formate as the hydrogen source through Asymmetric Transfer Hydrogenation-Dynamic Kinetic Resolution (ATH-DKR). Due to the neutral conditions employed, isoflavones with different substituents at the 2’-position of B-ring (H, OH, OMe and Br) were successfully reduced. Ten cis-3-phenylchroman-4-ols were selectively obtained (>20 : 1 dr) in good yields (up to 86 %) and excellent enantioselectivities (up to >99 : 1 er). The synthetic applications of these chiral compounds were also demonstrated. Enantioenriched isoflavanones were obtained under mild metal-free oxidation of the cis-3-phenylchroman-4-ols while pterocarpans were synthesized by two strategies: an acid-catalyzed cyclization and a novel approach based on a Pd-catalyzed C?O intramolecular cross-coupling reaction.

SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS

Disclosed are substituted heterocycle compounds including substituted pyrazoles, substituted pyrimidines, and substitute triazoles. The substituted heterocycles disclosed herein are shown to be useful in inhibiting c-MYC and may be utilized as therapeutics for treating cancer and cell proliferative disorders.

Development of 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs) from natural isoflavones, a new class of fluorescent scaffolds for biological imaging

Starting from 7-hydroxyisoflavones, we developed a new class of fluorescent scaffolds, 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs, MW ～ 205.19, λab ～ 350 nm, λem ～ 450 nm) via a trial and error process. AMHCs have the advantages of being a small molecular moiety, having strong fluorescence in basic buffers, reasonable solubility and stability, non-toxicity, and are conveniently linked to pharmacophores. AMHCs were successfully used in fluorescence microscopy imaging of cells and tissues. This journal is