89048-58-8

Basic information

• Product Name: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(4-morpholinylmethyl)-
• CAS NO: 89048-58-8
• Molecular Formula: C14H19NO5
• Molecular Weight: 281.309
• Mol File: 89048-58-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(4-morpholinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(4-morpholinylmethyl)-(89048-58-8)
• EPA Substance Registry System: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(4-morpholinylmethyl)-(89048-58-8)

Safety Data

• Hazardous Substances Data: 89048-58-8(Hazardous Substances Data)

Upstream product

• 72326-72-8 2-bromo-3,4,5-trimethoxy-1-methylbenzene 
• 6443-69-2 3,4,5-trimethoxytoluene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 89048-14-6 1-(bromomethyl)-2,3,4,5-tetramethoxy-6-methylbenzene 
• 110-91-8 morpholine 
• 89048-44-2 10-(2,3-dimethoxy-5-methyl-1,4-benzoquinon-6-yl)decanoyl-L-arginine 
• 89048-26-0 2,3-dimethoxy-5-methyl-6-morpholinomethylhydroquinone 
• 35896-58-3 2,3,4,5-tetramethoxytoluene 
• 3066-90-8 2,3-dimethoxy-5-methylbenzene-1,4-diol 
• 605-94-7 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 

Downstream Products

• 89048-59-9 2,3-dimethoxy-5-methyl-6-morpholinomethyl-1,4-benzoquinone hydrochloride 

Relevant articles and documents

Efficient synthesis and antioxidant activities of N-heterocyclyl substituted Coenzyme Q analogues

A new strategy for the efficient synthesis of C-5 heterocyclyl substituted Coenzyme Q analogues was developed by N-alkylation of bromomethylated quinone 11 with a series of amines 12 under metal-free conditions. In vitro antioxidant activities of these Coenzyme Q analogues were evaluated and compared with commercial antioxidant Coenzyme Q10 by employing DPPH assay. All these N-heterocyclyl substituted Coenzyme Q analogues are found to be exhibiting good antioxidant properties and may be used as potent antioxidants for combating oxidative stress.

Synthesis and antioxidant activities of Coenzyme Q analogues

A series of 2,3-dimethoxy-5-methyl-1,4-benzoquinones (Coenzyme Q) substituted at the C-6 position with various groups were designed and synthesized based on the Coenzyme Q10 as potent antioxidant. In vitro antioxidant activities of these compounds were evaluated and compared with commercial antioxidant Coenzyme Q10 employing DPPH assay. All these synthesized Coenzyme Q analogues are found to exhibit good antioxidant activities. Of which Compound 8b bearing a N-benzoylpiperazine group at the C-6 position showed more potent inhibition of DPPH radical than Coenzyme Q10. All these results suggested the applicability of the Coenzyme Q analogues as potent antioxidants for combating oxidative stress.

Effects of 6-(ω-substituted alkyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinones and related compounds on mitochondrial succinate and reduced nicotinamide adenine dinucleotide oxidase systems

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