89059-57-4

Basic information

• Product Name: 3-Cyclohexene-1-carboxylic acid, 4-(2-hydroxy-4-methoxyphenyl)-2-oxo-6-phenyl-, ethyl ester
• CAS NO: 89059-57-4
• Molecular Formula: C22H22O5
• Molecular Weight: 366.414
• Mol File: 89059-57-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Cyclohexene-1-carboxylic acid, 4-(2-hydroxy-4-methoxyphenyl)-2-oxo-6-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexene-1-carboxylic acid, 4-(2-hydroxy-4-methoxyphenyl)-2-oxo-6-phenyl-, ethyl ester(89059-57-4)
• EPA Substance Registry System: 3-Cyclohexene-1-carboxylic acid, 4-(2-hydroxy-4-methoxyphenyl)-2-oxo-6-phenyl-, ethyl ester(89059-57-4)

Safety Data

• Hazardous Substances Data: 89059-57-4(Hazardous Substances Data)

Upstream product

• 39273-61-5 (E)-1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 89059-49-4 3-(2-hydroxy-4-methoxyphenyl)-5-phenylcyclohex-2-en-1-one 

Relevant articles and documents

Synthesis of 3,5-Diaryl-6-carbethoxycyclohex-2-en-1-ones and 4,6-Diaryl-3,3a,4,5-tetrahydro-3(2H)-oxoindazoles and a Study of their Biological Activities

Four different chalcones (1a-d) have been subjected to Michael condensation with ethyl acetoacetate in the presence of either ethanolic piperidine or dry potassium carbonate in acetone and the resultant 3,5-diaryl-6-carbethoxy-cyclohex-2-en-1-ones (2a-d) converted into the corresponding 4,6-diaryl-3,3a,4,5-tetrahydro-3(2H)-oxoindazoles (3a-d) by heating with hydrazine hydrate in ethanolic acetic acid.These products have been characterised as acetates which are shown to exist as mixtures of 4a-d and 5a-d on the basis of their PMR data.The biological activities of 3a-d are also discussed.