89068-54-2

Basic information

• Product Name: 1H-Pyrrole-2,5-dione, 3,4-dimethyl-1-(4-methylphenyl)-
• CAS NO: 89068-54-2
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Mol File: 89068-54-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2,5-dione, 3,4-dimethyl-1-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,5-dione, 3,4-dimethyl-1-(4-methylphenyl)-(89068-54-2)
• EPA Substance Registry System: 1H-Pyrrole-2,5-dione, 3,4-dimethyl-1-(4-methylphenyl)-(89068-54-2)

Safety Data

• Hazardous Substances Data: 89068-54-2(Hazardous Substances Data)

Upstream product

• 18913-36-5 2-methyl-butadienoic acid 
• 7175-47-5 4-methylphenyl isocyanide 
• 81189-49-3 1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione 
• 74216-90-3 N-p-tolylmethylsuccinimide 
• 50-00-0 formaldehyd 
• 190728-72-4 3-Methyl-1-p-tolyl-4-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione 
• 766-39-2 2,3-Dimethylmaleic anhydride 
• 106-49-0 p-toluidine 
• 31519-20-7 2-hydroxy-2,3-dimethyl-succinic acid 
• 3120-12-5 3-methyl-1-(p-tolyl)-1H-pyrrole-2,5-dione 

Downstream Products

• 766-39-2 2,3-Dimethylmaleic anhydride 

Relevant articles and documents

Application of maleimide compound as chitin synthase inhibitor

The invention discloses an application of a maleimide compound as shown in a formula I. In the formula I, R0 is phenyl, benzyl, phenethyl, phenylpropyl, p-fluorophenyl, p-chlorophenyl, p-bromophenyl,p-methoxyphenyl, p-methylphenyl or p-hydroxyphenyl, R1 is hydrogen, methyl, phenyl or chlorine; and R2 is hydrogen, methyl, phenyl or chlorine. The provided maleimide compound has a good inhibition effect on chitin synthase.

An efficient synthesis of dimethylmaleic anhydride

A facile three-step synthesis of dimethylmaleic anhydride (8) with 74% overall yield has been described starting from maleimide 1, via methylmaleimide 4, using two Wittig reactions followed by an alkaline hydrolysis.