891392-78-2

Basic information

• Product Name: 1-(4-Ethyl-benzenesulfonyl)-1H-pyrrole
• CAS NO: 891392-78-2
• Molecular Weight: 235.307
• Mol File: 891392-78-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-Ethyl-benzenesulfonyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Ethyl-benzenesulfonyl)-1H-pyrrole(891392-78-2)
• EPA Substance Registry System: 1-(4-Ethyl-benzenesulfonyl)-1H-pyrrole(891392-78-2)

Safety Data

• Hazardous Substances Data: 891392-78-2(Hazardous Substances Data)

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 138-38-5 4-ethylbenzenesulfonamide 

Relevant articles and documents

1-arylsulfonyl-3-(α-hydroxybenzyl)-1H-pyrroles, a novel class of anti-HIV-1 reverse transcriptase inhibitors

Various 1-arylsulfonyl-3-(α-hydroxybenzyl)-1H-pyrroles were prepared by Friedel-Crafts reaction of 1-arylsulfonyl-1H-pyrroles with aroylchlorides in the presence of aluminum trichloride, followed by reduction of the ketones to the required carbinols. The compounds were identified as a novel class of non-nucleoside HIV-1 reverse transcriptase inhibitors characterized by the presence of a diarylcarbinol moiety, a chemical feature that strictly correlates with the anti-HIV-1 activity.