89226-83-5

Basic information

• Product Name: 1,2-Benzenedicarboxaldehyde, 4-fluoro-
• CAS NO: 89226-83-5
• Molecular Formula: C8H5FO2
• Molecular Weight: 152.125
• Mol File: 89226-83-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedicarboxaldehyde, 4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarboxaldehyde, 4-fluoro-(89226-83-5)
• EPA Substance Registry System: 1,2-Benzenedicarboxaldehyde, 4-fluoro-(89226-83-5)

Safety Data

• Hazardous Substances Data: 89226-83-5(Hazardous Substances Data)

Usage

Usage

Reactant in organic synthesis, fluorescent labeling reagent for amino acids and biomolecules

Derivative of

Phthalaldehyde

Structural feature

Fluorine atom at the 4-position of the benzene ring

Physical state

Yellow crystalline solid

Solubility

Sparingly soluble in water, soluble in organic solvents

Applications

Pharmaceutical and chemical industries, diagnostic tests, fluorescent labeling, synthesis of other compounds

Safety precautions

Handle and store with caution due to irritant and potentially toxic properties

Upstream product

• 452-64-2 3,4-dimethyl-fluorobenzene 
• 319-03-9 4-fluorophthalic anhydride 
• 320-97-8 4-fluorobenzene-1,2-dicarboxylic acid 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 
• 1258512-08-1 2-(1,3-dioxolan-2-yl)-5-fluorobenzaldehyde 
• 773097-04-4 2-(2-bromo-4-fluorophenyl)-1,3-dioxolane 
• 62558-08-1 4-fluoro-2-(hydroxymethyl)benzyl alcohol 

Downstream Products

• 1258512-43-4 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione 

Relevant articles and documents

FlICk (fluorescent isoindole crosslinking) for peptide stapling

The rigidification of peptide secondary structure via stapling is an important and enduring goal in the development of functional peptides for biochemical and pharmaceutical applications. In addition, the incorporation of fluorophores and chromophores has

Site-Selective Functionalization of (sp3)C?H Bonds Catalyzed by Artificial Metalloenzymes Containing an Iridium-Porphyrin Cofactor

The selective functionalization of one C?H bond over others in nearly identical steric and electronic environments can facilitate the construction of complex molecules. We report site-selective functionalizations of C?H bonds, differentiated solely by rem

NHC-catalyzed spiro bis-indane formation via domino stetter - Aldol - Michael and stetter - Aldol - Aldol reactions

Two novel domino NHC-catalyzed spirocyclizations are described herein, enabling the rapid construction of three new carbon - carbon bonds and a quaternary center with high diastereoselectivity. A variety of spiro bis-indane structures are assembled in a single step from simple o-phthaldialdehyde derivatives.