89237-29-6

Basic information

• Product Name: p-methoxyphenyl-1'cyano-1'dimethyl-2,3 cyclopentanone
• CAS NO: 89237-29-6
• Molecular Weight: 243.305
• Mol File: 89237-29-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-methoxyphenyl-1'cyano-1'dimethyl-2,3 cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: p-methoxyphenyl-1'cyano-1'dimethyl-2,3 cyclopentanone(89237-29-6)
• EPA Substance Registry System: p-methoxyphenyl-1'cyano-1'dimethyl-2,3 cyclopentanone(89237-29-6)

Safety Data

• Hazardous Substances Data: 89237-29-6(Hazardous Substances Data)

Upstream product

• 1120-73-6 2-methyl-2-cyclopenten-1-one 
• 1823-91-2 1-phenylethyl cyanide 
• 104-47-2 p-methoxybenzylnitrile 
• 71956-15-5 C₉H₈NO^(1-)*Li⁽¹⁺⁾ 
• 930-30-3 cyclopent-2-enone 
• 167320-57-2 lihio p-methoxyphenylacetonitrile 
• 74-88-4 methyl iodide 
• 106400-26-4 (4-Methoxy-phenyl)-(2-methyl-3-oxo-cyclopentyl)-acetonitrile 

Downstream Products

• 92778-11-5 (4-Methoxy-phenyl)-((6R,7R)-6-methyl-1,4-dioxa-spiro[4.4]non-7-yl)-acetonitrile 
• 92778-13-7 (2S,3R)-3-(4-Methoxy-benzoyl)-2-methyl-cyclopentanone 
• 92778-12-6 (4-Methoxy-phenyl)-((6R,7S)-6-methyl-1,4-dioxa-spiro[4.4]non-7-yl)-methanone 

Relevant articles and documents

STEREOSELECTIVE SYNTHESIS OF SOME CIS 2,3-DISUBSTITUTED CYCLANONES RING SIZE INFLUENCE ON THE STEREOSELECTIVITY OF 2-SUBSTITUTED ENDOCYCLIC ENOLATES PROTONATION

Conjugate addition of carbanionic reagents formed from aryl- or phenyl-thioacetonitriles 1a-c and 2 to 2-methyl and 2-phenyl 2-cyclohexenone or 2-methyl 2-cyclopentenone, followed by acidic quench, under kinetic control, leads to different ratios of cis and trans 2,3-disubstituted cyclanones according to ring size.From 2-methyl and 2-phenyl 2-cyclohexenone, the cis isomer is highly predominant (85 to 98percent).From 2-methyl 2-cyclopentanone a cis/trans mixture is obtained: the cis isomer only predominates when a bulky reagent (1c) is used (80percent); in the other cases a mixture of nearly 1:1 is obtained.

Voie d'acces aux methyl-2 aroyl-3 cyclanones trans

Conjugate addition of lithiated arylacetonitriles to α-cyclenones followed by "one pot" methyl iodide trapping in DME leads excusively to monoalkylated trans compounds.Oxydative decyanation of these adducts under phase transfer conditions allows an easy a