89242-75-1

Basic information

• Product Name: 3-Pyridinemethanol, a-2-propynyl-
• Synonyms: 3-Pyridinemethanol, a-2-propynyl-;1-(Pyridin-3-yl)but-3-yn-1-ol
• CAS NO: 89242-75-1
• Molecular Formula: C9H9NO
• Molecular Weight: 147.17386
• Mol File: 89242-75-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinemethanol, a-2-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinemethanol, a-2-propynyl-(89242-75-1)
• EPA Substance Registry System: 3-Pyridinemethanol, a-2-propynyl-(89242-75-1)

Safety Data

• Hazardous Substances Data: 89242-75-1(Hazardous Substances Data)

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 106-96-7 propargyl bromide 

Downstream Products

• 517907-62-9 (R)-1-(3-pyridyl)but-3-yn-1-ol 
• 517907-62-9 (S)-1-(3-pyridyl)but-3-yn-1-ol 
• 517907-54-9 (R)-1-(3-pyridyl)but-3-yn-1-yl acetate 

Relevant articles and documents

Chemoenzymatic synthesis of optically active heterocyclic homoallylic and homopropargylic alcohols

A chemoenzymatic methodology has been developed using indium-mediated allylation of heterocyclic aldehydes under aqueous conditions followed by Pseudomonas cepacia lipase-catalyzed enantioselective acylation of racemic homoallylic and homopropargylic alcohols in organic media. It is observed that the lipase immobilized on ceramic particles (PS-C Amano II) catalyzes the resolution in a highly enantioselective manner in less time as compared to the native enzyme (PS Amano). The approach provides new functionalized chiral synthons useful in the synthesis of natural and pseudonatural products.