89267-43-6 Usage
Description
5-(Ethoxycarbonyl)-2-(hydroxyMethyl-6-Methyl-4-(3-nitrophenyl)nicotinic Acid is a complex organic compound that serves as a metabolite of Nitrendipine, a dihydropyridine calcium channel blocker used in the treatment of hypertension and angina.
Uses
Used in Pharmaceutical Industry:
5-(Ethoxycarbonyl)-2-(hydroxyMethyl-6-Methyl-4-(3-nitrophenyl)nicotinic Acid is used as a metabolite for [application reason]. As a metabolite of Nitrendipine, it plays a role in the drug's pharmacological effects and may contribute to its therapeutic benefits in treating cardiovascular conditions such as hypertension and angina. Further research is needed to fully understand its specific contributions and potential applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 89267-43-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,6 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 89267-43:
(7*8)+(6*9)+(5*2)+(4*6)+(3*7)+(2*4)+(1*3)=176
176 % 10 = 6
So 89267-43-6 is a valid CAS Registry Number.
89267-43-6Relevant articles and documents
Synthesis method of nitrendipine metabolite
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Paragraph 0052; 0053, (2018/08/03)
The invention discloses a synthesis method of nitrendipine metabolite. The method takes 4-(benzyloxy)-3-ethyl oxo-butyrate and 3-hydroxypropionitrile as starting raw materials to synthesize the nitrendipine metabolite through 6-step reaction. A lot of experiments are carried out to screen optimal preparation steps and reaction conditions; a whole technology is reasonably designed and strong in operability; the chemical purity of the nitrendipine metabolite prepared by the synthesis method can reach 99 percent or more and the yield is high. The nitrendipine metabolite prepared by the synthesismethod provides a standard product for metabolic mechanism researches of a nitrendipine medicine and can be used for exploring a metabolic process of the medicine in organisms; the nitrendipine metabolite has a relatively good potential hypertension-resisting effect and has extremely application and research value in clinical pharmacokinetics researches.
