89284-05-9

Basic information

• Product Name: 4-AMINO-3-BROMO-5-NITROPYRIDINE
• Synonyms: 4-AMINO-3-BROMO-5-NITROPYRIDINE;4-AMino-3-nitro-5-broMopyridine;4-AMino-3-broMo-5-nitropy...;4-Amino-3-bromo-5-nitropyridine 97%
• CAS NO: 89284-05-9
• Molecular Formula: C₅H₄BrN₃O₂
• Molecular Weight: 218.00816
• Product Categories: Pyridine
• Mol File: 89284-05-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: 174-175℃
• Boiling Point: 346.5 °C at 760 mmHg
• Flash Point: 163.4 °C
• Appearance: /
• Density: 1.929
• Vapor Pressure: 5.72E-05mmHg at 25°C
• Refractive Index: 1.682
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-AMINO-3-BROMO-5-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3-BROMO-5-NITROPYRIDINE(89284-05-9)
• EPA Substance Registry System: 4-AMINO-3-BROMO-5-NITROPYRIDINE(89284-05-9)

Safety Data

• Hazardous Substances Data: 89284-05-9(Hazardous Substances Data)

Usage

General Description

4-Amino-3-bromo-5-nitropyridine is a chemical compound with the molecular formula C5H4BrN3O2. It is a yellow to orange solid that is primarily used as a building block in the synthesis of pharmaceuticals and agrochemicals. 4-Amino-3-bromo-5-nitropyridine is a substituted pyridine derivative, which makes it useful in the development of various organic compounds. It is known to have significant potential in medicinal chemistry because of its ability to serve as a precursor for the synthesis of diverse biologically active molecules. Additionally, it has been studied for its potential application in materials science and can be used as a reagent in organic synthesis. However, it is important to handle this chemical with care, as it is considered hazardous and should only be used by trained professionals in a controlled laboratory environment.

InChI:InChI=1/C5H4BrN3O2/c6-3-1-8-2-4(5(3)7)9(10)11/h1-2H,(H2,7,8)

Upstream product

• 26482-55-3 4-(nitroamino)pyridine 
• 504-24-5 4-aminopyridine 
• 170158-64-2 4-(N-bromo-N-nitro)aminopyridine 
• 15367-14-3 4-Nitramino-3-brom-pyridin 
• 1681-37-4 4-amino-3-nitropyridine 
• 31872-63-6 3-bromo-4-chloro-5-nitropyridine 
• 333-20-0 potassium thioacyanate 
• 64-19-7 acetic acid 
• 7726-95-6 bromine 

Downstream Products

• 4635-08-9 3,4-diamino-5-bromopyridine 
• 1305317-09-2 N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)benzophenone imine 
• 1305317-10-5 N-[2,3-bis(4-methoxyphenyl)pyrido[3,4-b]pyrazin-8-yl]benzophenone imine 
• 788821-74-9 8-amino-2,3-diphenylpyrido[3,4-b]pyrazine 
• 1305317-11-6 8-amino-2,3-bis(4-methoxyphenyl)pyrido[3,4-b]pyrazine 
• 1305317-14-9 N-(3-bromophenyl)-2,3-diphenylpyrido[3,4-b]pyrazin-8-amine 
• 1305317-15-0 N-(3-chloro-4-fluorophenyl)-2,3-diphenylpyrido[3,4-b]pyrazin-8-amine 
• 1305317-16-1 N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)-N'-ethylurea 
• 1305317-17-2 N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)-N'-phenylurea 
• 1305317-18-3 N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)-N'-(3-methoxyphenyl)urea 
• 1305317-19-4 N-(3-chlorophenyl)-N'-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)urea 
• 1305317-20-7 N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)urea 
• 1305317-22-9 N-[2,3-bis(4-methoxyphenyl)pyrido[3,4-b]pyrazin-8-yl]-N'-phenylurea 
• 1305317-24-1 N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)-N'-ethylthiourea 

Relevant articles and documents

FUSED RING COMPOUND, AND INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Provides a compound as shown in formula Ia or IB, a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a polymorph thereof, a metabolite thereof, a stereoisomer thereof, an tautomer thereof, or a prodrug thereof. The compound as a Wnt inhibitor and mesenchymal stem cell inducer, sox9, type I collagen, X. collagen, osteogenetic transcription gene and alkaline phosphatase one or more have a good inducing effect, which can then be used to prepare drugs for the treatment and / or improvement of related diseases and disorders.

PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY

Pyrazole compounds (I) for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a pyrazole compounds, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis Alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.

3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF

4-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of a 4-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.