89284-30-0

Basic information

• Product Name: 6-chloro-9H-purin-9-amine
• CAS NO: 89284-30-0
• Molecular Formula: C₅H₄ClN₅
• Molecular Weight: 169.5718
• Mol File: 89284-30-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 397.5°C at 760 mmHg
• Flash Point: 194.2°C
• Density: 1.95g/cm³
• Vapor Pressure: 1.58E-06mmHg at 25°C
• Refractive Index: 1.889
• CAS DataBase Reference: 6-chloro-9H-purin-9-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-9H-purin-9-amine(89284-30-0)
• EPA Substance Registry System: 6-chloro-9H-purin-9-amine(89284-30-0)

Safety Data

• Hazardous Substances Data: 89284-30-0(Hazardous Substances Data)

Usage

Type

Organic chemical compound

Derivative of

Adenine (a purine base found in DNA and RNA)

Applications

Pharmaceuticals, agrochemicals, materials science

Uses

Starting material in synthesis of pharmaceutical compounds, precursor to other chemicals, research tool in biochemistry and molecular biology studies

Potential effects

Investigates effects of chlorination on purine structure and function

Relevant articles and documents

Pyrrolidine Analogues of 2',3'-Dideoxynucleosides: Synthesis via 9-Aminopurines and 1-Aminopyrimidines

Analogues of 2',3'-dideoxynucleosides in which the tetrahydrofuran ring is replaced by a pyrrolidine ring linked to the base through an N-N bond have been prepared.The adenine 26, guanine 25 and and hypoxanthine 27 compounds were synthesised via 9-aminopurines.Corresponding derivatives of 5-iodouracil 31, 5-chlorouracil 33 and 5-chlorocytosine 35 were prepared by substitution at the 5-position of hydroxy protected uracil derivatives.Enantiomers, 40a and 40b, of the pyrrolidine analogue of dideoxycytidine were prepared from 1-aminocytosine.The novel N-aminobases 9-aminoadenine 10, 1-aminocytosine 13 and 1-aminothymine 15 are described.