893447-27-3

Basic information

• Product Name: Pyrazolo[1,5-a]pyrimidine, 7-chloro-2-cyclopropyl-5-phenyl-
• CAS NO: 893447-27-3
• Molecular Formula: C15H12ClN3
• Molecular Weight: 269.733
• Mol File: 893447-27-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrazolo[1,5-a]pyrimidine, 7-chloro-2-cyclopropyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazolo[1,5-a]pyrimidine, 7-chloro-2-cyclopropyl-5-phenyl-(893447-27-3)
• EPA Substance Registry System: Pyrazolo[1,5-a]pyrimidine, 7-chloro-2-cyclopropyl-5-phenyl-(893447-27-3)

Safety Data

• Hazardous Substances Data: 893447-27-3(Hazardous Substances Data)

Downstream Products

• 893445-67-5 C₂₁H₁₈N₄O₃S 
• 893447-42-2 4-(2-cyclopropyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-ylamino)benzoic acid tert-butyl ester 

Relevant articles and documents

Pyrazolo [1,5-A] pyrimidine adenosine A2a receptor antagonists

Compounds having the structural formula I are disclosed, wherein A is alkylene, or optionally substituted arylene, cycloalkylene or heteroaryldiyl; X is —C(O)— or —S(O)2—; R1 is alkyl or cycloalkyl; R2 is hydrogen, halo or —CN; R3 is hydrogen or alkyl; R4 is hydrogen, alkyl, alkoxy, hydroxyalkyl, aminoalkyl-, cycloalkyl, heterocycloalkyl, heterocycloalkyl substituted by alkyl, optionally substituted arylalkyl or optionally substituted heteroarylalkyl; or R3 and R4, form an optionally substituted 5-7 membered ring, said ring optionally comprising an additional heteroatom ring member; R7 is alkyl, optionally substituted phenyl, optionally substituted heteroaryl, cycloalkyl, halo, morpholinyl, optionally substituted piperazinyl, or optionally substituted azacycloalkyl. Also disclosed is the use of the compounds in the treatment of Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, pharmaceutical compositions comprising them and kits comprising the components of the combinations.