89352-67-0

Basic information

• Product Name: ICI 174,864
• Synonyms: ICI 174,864;N,N-DIALLYL-TYR-AIB-AIB-PHE-LEU;ICI-174,864 SELECTIVE GAMMA OPIOI;N,N-diallyl-tyrosyl-alpha-aminoisobutyric acid-phenylalanyl-leucine;N,N-Di(2-propenyl)-L-Tyr-2-methyl-L-Ala-L-Phe-L-Leu-OH;L-Leucine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-L-phenylalanyl)-;L-Leucine, N,N-di-2-propenyl-L-tyrosyl-2-methylalanyl-L-phenylalanyl-;N,N-Diallyl-Tyr-aib-Phe-Leu
• CAS NO: 89352-67-0
• Molecular Formula: C38H53N5O7
• Molecular Weight: 691.86
• Mol File: 89352-67-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 892.7 °C at 760 mmHg
• Flash Point: 493.7 °C
• Appearance: white/solid
• Density: 1.16 g/cm³
• Vapor Pressure: 3.16E-34mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: −20°C
• CAS DataBase Reference: ICI 174,864(CAS DataBase Reference)
• NIST Chemistry Reference: ICI 174,864(89352-67-0)
• EPA Substance Registry System: ICI 174,864(89352-67-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 89352-67-0(Hazardous Substances Data)

Usage

Description

ICI 174,864 is a highly selective and potent antagonist for the opioid delta receptor, specifically designed to target and block the delta-opioid receptors in the body. This unique property allows it to have potential applications in various fields, particularly in the medical and pharmaceutical industries.

Uses

Used in Pharmaceutical Industry:
ICI 174,864 is used as a selective delta receptor antagonist for the development of therapeutic agents targeting the opioid delta receptors. Its ability to selectively block these receptors can be utilized in the treatment of various conditions, such as pain management, addiction, and other disorders related to the opioid system.
Used in Pain Management:
ICI 174,864 is used as a pain management agent, as its antagonistic effect on the delta-opioid receptors can help in reducing pain sensations without causing the typical side effects associated with traditional opioid medications. This selective targeting can lead to safer and more effective pain relief options.
Used in Addiction Treatment:
ICI 174,864 is used as an addiction treatment agent, as its antagonistic properties can help in reducing the rewarding effects of opioids and other addictive substances. By blocking the delta-opioid receptors, it can potentially decrease cravings and withdrawal symptoms, making it a valuable tool in addiction recovery programs.
Used in Research:
ICI 174,864 is used as a research tool for studying the role of delta-opioid receptors in various physiological and pathological processes. Its high selectivity for these receptors makes it an ideal candidate for investigating the mechanisms of action and potential therapeutic targets in the opioid system.

InChI:InChI=1/C34H46N4O6/c1-7-18-38(19-8-2)29(22-25-14-16-26(39)17-15-25)31(41)37-34(5,6)33(44)36-27(21-24-12-10-9-11-13-24)30(40)35-28(32(42)43)20-23(3)4/h7-17,23,27-29,39H,1-2,18-22H2,3-6H3,(H,35,40)(H,36,44)(H,37,41)(H,42,43)/t27-,28-,29-/m0/s1