893566-72-8

Basic information

• Product Name: TERT-BUTYL 6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE
• Synonyms: TERT-BUTYL 6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE;tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoli;N-Boc-1,2,3,4-tetrahydroisoquinoline-6-boronic acid pinacol ester;tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxyl;2(1H)-Isoquinolinecarboxylic acid,3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-,1,1-dimethylethyl ester;2-Boc-3,4-dihydro-1H-isoquinoline-6-boronic acid pinacol ester;tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carbo
• CAS NO: 893566-72-8
• Molecular Formula: C₂₀H₃₀BNO₄
• Molecular Weight: 359.27
• Product Categories: CHIRAL CHEMICALS
• Mol File: 893566-72-8.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 462.2°C at 760 mmHg
• Flash Point: 233.3°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 1.01E-08mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: TERT-BUTYL 6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE(893566-72-8)
• EPA Substance Registry System: TERT-BUTYL 6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE(893566-72-8)

Safety Data

• Hazardous Substances Data: 893566-72-8(Hazardous Substances Data)

Usage

Uses

tert-?Butyl 6-?(4,?4,?5,?5-?tetramethyl-?1,?3,?2-?dioxaborolan-?2-?yl)?-?3,?4-?dihydroisoquinoline-?2(1H)?-?carboxylate is a reactant in the synthesis of tyrosine kinase inhibitors in the treatment of proliferative diseases.

InChI:InChI=1/C20H30BNO4/c1-18(2,3)24-17(23)22-11-10-14-12-16(9-8-15(14)13-22)21-25-19(4,5)20(6,7)26-21/h8-9,12H,10-11,13H2,1-7H3

Upstream product

• 226942-29-6 6-bromo-1,2,3,4-tetrahydroisoquinoline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 158984-83-9 N-tert-butoxycarbonyl-6-hydroxy-1,2,3,4-tetrahydroisoquinoline 
• 59839-23-5 6-hydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 22246-12-4 6-methoxy-1,2,3,4-tetrahydro-1-oxoisoquinoline 
• 158984-84-0 6-trifluoromethanesulfonyloxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 893566-74-0 6-bromo-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline 
• 73183-34-3 bis(pinacol)diborane 
• 893566-75-1 tert-butyl 8-bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate 
• 34784-05-9 6-bromo-isoquinoline 
• 215798-19-9 6-bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride 

Downstream Products

• 1258440-75-3 1,1-dimethylethyl 6-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,3,4-thiadiazol-2-yl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate 
• 1258440-17-3 2-[(1-methylethyl)oxy]-5-[5-(1,2,3,4-tetrahydro-6-isoquinolinyl)-1,3,4-thiadiazol-2-yl]benzonitrile 
• 1258852-58-2 3-[6-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,3,4-thiadiazol-2-yl)-3,4-dihydro-2(1H)-isoquinolinyl]propanamide 
• 1613147-78-6 (R)-5-(2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 

Relevant articles and documents

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