893746-80-0Relevant articles and documents
Nickel-Catalyzed Asymmetric Propargylic Amination of Propargylic Carbonates Bearing an Internal Alkyne Group
Watanabe, Kouichi,Miyazaki, Yusuke,Okubo, Masataka,Zhou, Biao,Tsuji, Hiroaki,Kawatsura, Motoi
, p. 5448 - 5451 (2018)
We have achieved the nickel-catalyzed asymmetric propargylic amination of propargylic carbonates bearing an internal alkyne group. A wide variety of propargylic carbonates and N-methylaniline derivatives were tolerated under the reaction conditions, providing the corresponding chiral propargylic amines in up to 97% yield with up to 97% ee.