893755-11-8 Usage
Description
[1-(3-methoxybenzyl)piperidin-4-yl]methylamine is a complex chemical compound featuring a piperidine ring with a methoxybenzyl group attached, and a methylamine group connected to the piperidine ring. [1-(3-methoxybenzyl)piperidin-4-yl]methylamine holds potential pharmaceutical applications due to the presence of a piperidine ring, which is a common structural element in numerous bioactive molecules. The methoxybenzyl group adds to the compound's properties, possibly enhancing its lipophilicity and enabling interactions with specific biological targets. The unique and intricate structure of [1-(3-methoxybenzyl)piperidin-4-yl]methylamine makes it a promising candidate for further research and investigation.
Uses
Used in Pharmaceutical Industry:
[1-(3-methoxybenzyl)piperidin-4-yl]methylamine is used as a potential pharmaceutical compound for its bioactive properties. The presence of the piperidine ring, a common structural element in many bioactive molecules, suggests that this compound may have therapeutic applications. Additionally, the methoxybenzyl group may provide specific interactions with biological targets, further enhancing its potential for pharmaceutical use.
Used in Drug Design and Development:
In the field of drug design and development, [1-(3-methoxybenzyl)piperidin-4-yl]methylamine can be utilized as a structural template or a building block for creating new drugs. Its unique structure and potential interactions with biological targets make it a valuable asset for designing novel therapeutic agents.
Used in Chemical Research:
[1-(3-methoxybenzyl)piperidin-4-yl]methylamine is also used as a subject of study in chemical research. Its complex structure and potential pharmaceutical applications make it an interesting compound for scientists to explore, potentially leading to new discoveries and advancements in the field of chemistry.
Overall, [1-(3-methoxybenzyl)piperidin-4-yl]methylamine is a versatile compound with potential applications in various industries, particularly in the pharmaceutical sector. Its unique structure and properties make it a valuable candidate for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 893755-11-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,3,7,5 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 893755-11:
(8*8)+(7*9)+(6*3)+(5*7)+(4*5)+(3*5)+(2*1)+(1*1)=218
218 % 10 = 8
So 893755-11-8 is a valid CAS Registry Number.
893755-11-8Relevant articles and documents
Discovery and Biological Evaluation of N-Methyl-pyrrolo[2,3- b]pyridine-5-carboxamide Derivatives as JAK1-Selective Inhibitors
Park, Eunsun,Lee, Sun Joo,Moon, Heegyum,Park, Jongmi,Jeon, Hyeonho,Hwang, Ji Sun,Hwang, Hayoung,Hong, Ki Bum,Han, Seung-Hee,Choi, Sun,Kang, Soosung
, p. 958 - 979 (2021/02/01)
Janus kinase 1 (JAK1) plays a key role in most cytokine-mediated inflammatory and autoimmune responses through JAK/STAT signaling; thus, JAK1 inhibition is a promising therapeutic strategy for several diseases. Analysis of the binding modes of current JAK inhibitors to JAK isoforms allowed the design of N-alkyl-substituted 1-H-pyrrolo[2,3-b] pyridine carboxamide as a JAK1-selective scaffold, and the synthesis of various methyl amide derivatives provided 4-((cis-1-(4-chlorobenzyl)-2-methylpiperidin-4-yl)amino)-N-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxamide (31g) as a potent JAK1-selective inhibitor. In particular, the (S,S)-enantiomer of 31g (38a) exhibited excellent potency for JAK1 and selectivity over JAK2, JAK3, and TYK2. On investigating the effect of 31g on hepatic fibrosis, it was found that it reduces the proliferation and fibrogenic gene expression of TGF-β-induced hepatic stellate cells (HSCs). Specifically, 31g significantly inhibited TGF-β-induced migration of HSCs at 0.25 μM in wound-healing assays.
