89376-18-1

Basic information

• Product Name: Benzenesulfonyl chloride, 2-(phenylmethoxy)-
• Synonyms: 2-benzyloxy-benzenesulfonyl chloride;benzyloxyphenylsulphonyl chloride;2-benzyloxy-phenyl-sulfonyl chloride
• CAS NO: 89376-18-1
• Molecular Formula: C13H11ClO3S
• Molecular Weight: 282.748
• Mol File: 89376-18-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl chloride, 2-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl chloride, 2-(phenylmethoxy)-(89376-18-1)
• EPA Substance Registry System: Benzenesulfonyl chloride, 2-(phenylmethoxy)-(89376-18-1)

Safety Data

• Hazardous Substances Data: 89376-18-1(Hazardous Substances Data)

Upstream product

• 31575-75-4 2-bromophenyl benzyl ether 
• 109-72-8 n-butyllithium 

Downstream Products

• 475213-25-3 (S)-3-(2-benzyloxy-benzenesulfonylamino)-N-methoxy-N-methyl-succinamic acid tert-butyl ester 
• 190661-71-3 1-N-(N-Boc-leucinyl)-amino-3-N-(2-benzyloxy phenyl-sulfonyl)-amino-propan-2-ol 

Relevant articles and documents

Arylsulfonamide ethers, and methods of use thereof

Novel arylsulfonamide ether compounds and pharmaceutical compositions thereof are described. The use of the novel arylsulfonamide ether compounds and pharmaceutical compositions thereof as inhibitors of interleukin-1β converting enzyme and other cysteine proteases in the ICE family is also decribed. In addition, methods of treating stroke, inflammatory diseases, septic shock, repurfusion injury, Alzheimer's disease, and shigellosis using a compound of the invention or a pharmaceutical composition thereof are described.

PROTEASE INHIBITORS

Disclosed herein is a compound of the formula STR1 known as 2-[N-(N-benzyloxycarbonyl-L-leucinyl)]-2'-[N'-[4-(N,N-dimethylaminomethyl) benzyloxy]carbonyl-L-leucinyl]carbohydrazide; and pharmaceutically acceptable salts, hydrates and solvates thereof.