895136-26-2

Basic information

• Product Name: C₂₈H₂₉N₅O₄
• Synonyms: C₂₈H₂₉N₅O₄
• CAS NO: 895136-26-2
• Molecular Weight: 499.569
• Mol File: 895136-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₉N₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₉N₅O₄(895136-26-2)
• EPA Substance Registry System: C₂₈H₂₉N₅O₄(895136-26-2)

Safety Data

• Hazardous Substances Data: 895136-26-2(Hazardous Substances Data)

Upstream product

• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 74853-07-9 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl ]-phenyl]-3H-1,2,4-triazol-3-one 

Relevant articles and documents

TRIAZOLONE, TETRAZOLONE AND IMIDAZOLONE DERIVATIVES FOR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS

The present invention concerns substituted triazolone, tetrazolone and imidazolone derivatives according to the general Formula (I) a pharmaceutically acceptable acid or base addition salt thereof, a stereochemically isomeric form thereof, an N-oxide form thereof or a quaternary ammonium salt thereof, wherein the variables are defined in Claim 1, having selective α2C-adrenoceptor antagonist activity. It further relates to their preparation, compositions comprising them and their use as a medicine. The compounds according to the invention are usefull for the prevention and/or treatment of central nervous system disorders, mood disorders, anxi- ety disorders, stress-related disorders associated with depression and/or anxiety, cognitive disorders, personality disorders, schizoaffective disorders, Parkinson's disease, dementia of the Alzheimer's type, chronic pain conditions, neurodegenerative diseases, addiction disorders, mood disorders and sexual dysfunction.